Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-27T18:24:26.307Z Has data issue: false hasContentIssue false
  • English
  • Français

Polycaprolactone/α-Alumina and Hydroxyapatite-based Micro- and Nano- Structured Hybrid Fibers

Published online by Cambridge University Press:  25 June 2013

Simón Y. Reyes-Lopéz ,
Bonifacio Alvarado-Tenorio  and
Ángel Romo-Uribe
Simón Y. Reyes-Lopéz
Affiliation:
Departamento de Ciencias Químico-Biológicas, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Chihuahua 32310, MEXICO.
Bonifacio Alvarado-Tenorio*
Affiliation:
Departamento de Ciencias Químico-Biológicas, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Chihuahua 32310, MEXICO.
Ángel Romo-Uribe
Affiliation:
Lab. de Nanopolímeros y Coloides, Instituto de Ciencias Físicas, Universidad Nacional Autónoma de México, Cuernavaca Mor. 62210, MEXICO.
*
*To whom correspondence should be addressed: [email protected]
Get access

Abstract

The micro- and nanostructured phase behavior of non-woven hybrid electrospun fibers of Polycaprolactone (PCL-f), Polycaprolactone/α-Alumina (PCL/AA) and Polycaprolactone/Hydroxyapatite (PCL/HA) were elucidated. Nanoparticles of Hydroxyapatite featured 7-20 nm while α-Alumina was 500 nm in average size. Analysis by Transmission Electron Microscopy (TEM), Small-Angle Light Scattering (SALS), Polarized Optical Microscopy (POM) and Differential Scanning Calorimetry (DSC) enabled us to suggest a simple structural model for the series of hybrid fibers. PCL with a molecular weight of 70,000 g/mol was dissolved in chloroform. POM exhibited qualitative birefringent regions for all samples at the microscale level. Furthermore, polarized light distinguished between amorphous and micro-ordered structures along the fibers. On the other hand, SALS patterns suggested a needle-like morphology for all fibers. The influence of both, Hydroxyapatite and α-Alumina, was apparent in the SALS patterns of the PCL semicrystalline phase. Thermal analysis by DSC showed that the crystalline phase of PCL was disrupted by the presence of the inorganic nanoparticles. TEM micrographs showed that Hydroxyapatite and α-Alumina nanoparticles were embedded along the structure of PCL microfibers.

Keywords

biomaterialmicrostructurenanostructure
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1569: Symposium NN – Advanced Materials for Biological and Biomedical Applications , 2013 , pp. 185 - 191
Copyright
Copyright © Materials Research Society 2013 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Woodruff, M.A., Lange, C., Reichert, J., et al. , Materials Today 15, 430 (2012).CrossRefGoogle Scholar
Megelski, S., Stephens, J.S., Chase, D.B. and Rabolt, J.F., Macromolecules 35, 8456 (2002).CrossRefGoogle Scholar
Bognitzki, M., Czado, W., Frese, T., et al. , Adv. Mater. 13, 70 (2001).3.0.CO;2-H>CrossRefGoogle Scholar
Kim, G.H., Han, H., Park, J.H. and Kim, W.D., Polym. Eng. Sci. 47, 707 (2007).CrossRefGoogle Scholar
Vargas-Villagrán, H., Terán-Salgado, E., Domínguez-Díaz, M., Flores, O., Campillo, B., Flores, A., and Romo-Uribe, A., Mater. Res. Soc. Symp. Proc. Vol. 1376. (2012). DOI: 10.1557/opl.2012.285 Google Scholar
Dominguez-Diaz, M., Flores, A., Cruz-Silva, R., and Romo-Uribe, A., Mater. Res. Soc. Symp. Proc. 1466 (2012), DOI: 10.1557/opl.2012.1256 CrossRefGoogle Scholar
Fujihara, K., Kotaki, M. and Ramakrishna, S., Biomaterials 26, 4139 (2005).CrossRefGoogle Scholar
Jeong, S.I., Ko, E.K., Yum, J., Jung, C.H., Lee, Y.M. and Shin, H., Macromol. Biosci. 8, 328 (2008).CrossRefGoogle Scholar
Sedel, L. and Raould, A., Proc. Inst. Mech. Eng. [H], 221, 21 (2007).CrossRefGoogle Scholar
Rokusek, D., Davitt, C., Bandyopadhyay, A., Bose, S. and Hosick, H.L., J. Biomed. Mater. Res. Part A 75, 588 (2005).CrossRefGoogle Scholar
Romo-Uribe, A., Alvarado-Tenorio, B. and Romero-Guzmán, M.E., Rev. LatinAm. Metal. Mat., 30(1), 190 (2010).Google Scholar
Stein, R. S. Newer Methods of Polymer Characterization. New York: Interscience Publishers, (1964) p. 155.Google Scholar
Katoh, Y. and Okamoto, M., Polymer 50, 4718 (2009).CrossRefGoogle Scholar
Crescenzi, V., Manzini, G., Calzolari, G. and Borri, C., Eur. Polym. J. 8, 449 (1972).CrossRefGoogle Scholar