Multiscale mechanics of biological, bioinspired, and biomedical materials. Recent decades have seen a growing interest in applying mechanical property measurement protocols to biological materials or materials mimicking or replacing biological tissue. This issue highlights different approaches to the challenge of extending theoretical and applied mechanics to the level needed for satisfying and capturing biological materials. The cover shows progressive decrimping of collagen fibers in the adventitia of a rabbit carotid artery. The same area was imaged using confocal microscopy for different pressure steps from 0 mmHg to 140 mmHg. The image is a result of a joint collaboration between the groups of Frans van de Vosse at Eindhoven University of Technology and Nikos Stergiopulos at the Swiss Federal Institute of Technology, Lausanne. See the technical theme that begins on page 309.