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Imaging Carbon Nanoparticles in Cells

Published online by Cambridge University Press:  14 March 2018

Mhairi Gass  and
Alexandra Porter
Mhairi Gass*
Affiliation:
SuperSTEM, Daresbury Laboratory, Daresbury, U.K.
Alexandra Porter
Affiliation:
Imperial College London, London, U.K.
*
[email protected]

Extract

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The application of nanotechnology in disciplines as varied as medicine and electronics is advancing rapidly with carbon nanoparticles (CNPs) such as fullerenes (C60) and nanotubes at the forefront. However, a lack of understanding of the interaction of such small structures with cellular material has resulted in concerns over their impact on human health and since the individual structures have a diameter of ~1 nm they are potentially small enough to penetrate through ion channels or diffuse through pores in the nuclear membrane. Assessing their toxicity is imperative. In response to these concerns there has been an increase in the number of papers addressing the toxicity of carbon nanoparticles over the last few years but much of this data appears contradictory. It is therefore essential to understand how the human body interacts with CNPs and more specifically to elucidate pathways by which CNPs enter the cell and their distribution within.

Type
Research Article
Information
Microscopy Today , Volume 16 , Issue 1 , January 2008 , pp. 42 - 47
Copyright
Copyright © Microscopy Society of America 2008

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