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Developments Towards Imaging Nanoscale Biology with XFELs: Some Recent Examples and a Glance to the Future

Published online by Cambridge University Press:  10 August 2018

Adrian P. Mancuso*
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Andrew Aquila
Affiliation:
SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park (CA)94025, USA
Richard Bean
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Johan Bielecki
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Carsten Fortmann-Grote
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Klaus Giewekemeyer
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Yoonhee Kim
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Ruslan Kurta
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Romain Letrun
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Masoud Mehrjoo
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Marc Messerschmidt
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany BioXFEL Science and Technology Center, Buffalo, NY, USA
Grant Mills
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany ARC Centre of Advanced Molecular Imaging, Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Victoria3086, Australia
Adam Round
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany Faculty of Natural Sciences, Keele University, Staffordshire, ST5 5BG, UK
Tokushi Sato
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany Center for Free Electron Laser Science, Deutsches Elektronen-Synchrotron, NotkestraBe 85, 22607Hamburg, Germany
Joachim Schulz
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Marcin Sikorski
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
Stephan Stern
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany Center for Free Electron Laser Science, Deutsches Elektronen-Synchrotron, NotkestraBe 85, 22607Hamburg, Germany
Patrik Vagovic
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany Center for Free Electron Laser Science, Deutsches Elektronen-Synchrotron, NotkestraBe 85, 22607Hamburg, Germany
Thomas Tschentscher
Affiliation:
European X-ray Free Electron Laser Facility GmbH, Holzkoppel 4, 22869, Schenefeld, Germany
*
* Corresponding author, [email protected]

Abstract

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Type
Abstract
Copyright
© Microscopy Society of America 2018 

Footnotes

a

Now at Deutsches Elektronen-Synchrotron, NotkestraBe 85, 22607 Hamburg, Germany

References

[1] Aquila, A., et al, Struct. Dyn. 2, 041701 2015.Google Scholar
[2] Altarelli, M. Mancuso, A. P. Philosophical Transactions of the Royal Society of London B: Biological Sciences 369, 20130311 2014.Google Scholar
[3] Neutze, R., Wouts, R., van der Spoel, D., Weckert, E. Hajdu, J. Nature 406, 752 2000.Google Scholar
[4] Chapman, H. N., Barty, A., Bogan, M., Boutet, S., Frank, M., Hau-Riege, S., Marchesini, S., Woods, B., Bajt, S. Benner, W. Nature Physics 2, 839 2006.CrossRefGoogle Scholar
[5] Mancuso, A. P., Yefanov, O. M. Vartanyants, I. A. Journal of Biotechnology 149, 229 2010.CrossRefGoogle Scholar
[6] Seibert, M. Marvin, et al Journal of Physics B: Atomic. Molecular and Optical Physics 43, 194015 2010.Google Scholar
[7] Ekeberg, T., et al., Phys. Rev. Lett. 114, 098102 2015.Google Scholar
[8] Kurta, R. P., et al, Phys. Rev. Lett. 119, 237 2017.CrossRefGoogle Scholar
[9] Tschentscher, T., et al, Applied Sciences 7(6), 592635, 2017.Google Scholar
[10] Yoon, C. H., et al, Sci. Rep. 1 2016.Google Scholar
[11] Fortmann-Grote, C., et al, arXiv Preprint arXiv 1610, 05980 2016.Google Scholar
[12] Fortmann-Grote, C., et al, IUCrJ 4, 560 2017.CrossRefGoogle Scholar
[13] Giewekemeyer, K., et al, in preparation.Google Scholar
[14] Kam, Z. Macromolecules 10, 927 1977.Google Scholar
[15] Mehrjoo, M., et al, Opt Express 25, 17892 2017.Google Scholar
[16] Mancuso, A. P., et al, Technical Design Report Scientific Instrument Single Particles, Clusters, andBiomolecules (SPB) 2013) doi: 10.3204/XFEL.EU/TR-2013-004.Google Scholar
[17] Hantke, M. F Nature Photonics 8 943 2014) ). & M. F. Hantke, et al, submitted.Google Scholar
[18] Bean, R. J., et al, Journal of Optics 18, 074011 2016.Google Scholar
[19] Greiffenberg, D. J Instrum 7, C01103 2012.Google Scholar
[20] The authors acknowledge the engineering and technical contributions of the SPB/SFX engineers and technicians, namely Thomas Dietze, Alexis Legrand, Felix Lemcke, Luis Lopez, Bradley Manning, Nadja Reimers, Philipp Schutt, Cedric Signe Takem, Andrew Stawniczy and Prasad Thute. The SFX User Consortium is thanked for providing valuable input as well as part of the funding for the SPB/SFX instrument. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 654220. Funding has also been provided by the NSF STC Award 'BioXFEL' (1231306)..Google Scholar