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The Arrangement of Microtubules in the Platelet Marginal Band

Published online by Cambridge University Press:  30 July 2020

Juleen Dickson ,
Joshua Strauss ,
Wenchen Chen ,
Elizabeth Wright  and
Renhao Li
Juleen Dickson
Affiliation:
University of Wisconsin-Madison, Madison, Wisconsin, United States
Joshua Strauss
Affiliation:
University of North Carolina - Chapel Hill, Chapel Hill, North Carolina, United States
Wenchen Chen
Affiliation:
Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, Georgia, United States
Elizabeth Wright
Affiliation:
University of Wisconsin-Madison, Madison, Wisconsin, United States
Renhao Li
Affiliation:
Aflac Cancer and Blood Disorders Center, Emory University School of Medicine, Atlanta, Georgia, United States

Abstract

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Type
Biomedical and Pharmaceutical Research on the Development, Diagnosis, Prevention, and Treatment of Diseases
Information
Microscopy and Microanalysis , Volume 26 , Supplement S2 , August 2020 , pp. 822 - 824
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Copyright
Copyright © Microscopy Society of America 2020

References

Shin, E.-K., et al. ., Platelet Shape Changes and Cytoskeleton Dynamics as Novel Therapeutic Targets for Anti-Thrombotic Drugs. Biomolecules & therapeutics, 2017. 25(3): p. 223-230.10.4062/biomolther.2016.138CrossRefGoogle ScholarPubMed
Dmitrieff, S., et al. ., Balance of microtubule stiffness and cortical tension determines the size of blood cells with marginal band across species. Proc Natl Acad Sci U S A, 2017. 114(17): p. 4418-4423.10.1073/pnas.1618041114CrossRefGoogle ScholarPubMed
Höög, J.L., et al. ., Electron tomography reveals a flared morphology on growing microtubule ends. Journal of Cell Science, 2011. 124(5): p. 693.10.1242/jcs.072967CrossRefGoogle ScholarPubMed
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This research was supported in part by funds from the University of Wisconsin, Madison, Emory University, Children's Healthcare of Atlanta, the Emory Center for AIDS Research, the Georgia Research Alliance, the National Science Foundation (0923395) to E.R.W.; and National Institutes of Health grant R21HL146299 to E.R.W. and R.L. The authors gratefully acknowledge use of facilities and instrumentation at the Emory University Robert P. Apkarian Integrated Electron Microscopy Coreand at the UW-Madison Wisconsin Centers for Nanoscale Technology (wcnt.wisc.edu) partially supported by the NSF through the University of Wisconsin Materials Research Science and Engineering Center (DMR-1720415).Google Scholar