Hostname: page-component-848d4c4894-sjtt6 Total loading time: 0 Render date: 2024-07-01T01:15:43.553Z Has data issue: false hasContentIssue false
  • English
  • Français

Prodromal stage of late-onset psychosis

Published online by Cambridge University Press:  01 September 2022

V. Pochueva ,
V. Sheshenin ,
M. Savina  and
T. Safarova
V. Pochueva*
Affiliation:
FSBSI “Mental Health Research Centre”, Geriatric Psychiatry, Moscow, Russian Federation
V. Sheshenin
Affiliation:
FSBSI “Mental Health Research Centre”, Geriatric Psychiatry, Moscow, Russian Federation
M. Savina
Affiliation:
FSBSI “Mental Health Research Centre”, Geriatric Psychiatry, Moscow, Russian Federation
T. Safarova
Affiliation:
FSBSI “Mental Health Research Centre”, Geriatric Psychiatry, Moscow, Russian Federation
*
*Corresponding author.

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

Prodromal stage of psychosis may be an aim of prevention first episode psychosis. In late-onset psychosis it’s low described.

Objectives

The aim of this investigation is to describe prodromal phase of late-onset psychosis and their connection with psychopathology.

Methods

74 women with late-onset psychosis (age 64,3±6,7) - late-onset schizophrenia (LOS) (n=49, age 63±8,4), schizoaffective disorder (n=17, age 62,4±6,5), late onset delusion disorder (LoDD) (n=8, age 76,6±4,3) underwent clinical assessment (SOPS, PANSS, HAMD-17), cognitive examination (MMSE, MoCA), structured interviewing on life-time pathology. Spearman’s rho statistics was used.

Results

LOP patients have low prodromal symptoms according to the SOPS score. In LOS patients middle score of SOPS is 18±8,5, in schizoaffective patients middle score of SOPS is 12,3±6,8, and for LoDD SOPS is 13,4 ±4,6. Prodromal disturbances are represented mainly by fragmentary paranoid ideas, thoughts of unusual content, acoasms and affective fluctuations. In LOS patients SOPS negative subscale correlate with HAMD (r=0,384, p<0,05), desorganisation subscale correlate with PANSS common psychopathology subscale (r=0,32, p<0,05) and total PANSS (r=0,28, p<0,05), generous subscale and common SOPS correlate with HAMD (r=0,29, r=0,3, p<0,05). For patients with schizoaffective disorder there is no correlations, and in patients with LoDD SOPS desorganisation subscale negative correlate with PANSS negative subscale (r=-0,71, p<0,05).

Conclusions

In patients with late psychoses, the severity of disorders in the prodromal period is minimal. However, prodromal features are associated with the psychopathology.

Disclosure

No significant relationships.

Keywords

Late-onset psychosislate onset schizophreniaprodromalfirst episod psychosis
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S175
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
Submit a response

Comments

No Comments have been published for this article.