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Serotypes of trachoma agent isolated in The Gambia: with an observation on the relation between serotype and morphology

Published online by Cambridge University Press:  15 May 2009

J. Sowa ,
L. H. Collier  and
Shiona Sowa
J. Sowa
Affiliation:
Medical Research Council Trachoma Unit, MRC Laboratories, Fajara, The Gambia and The Lister Institute of Preventive Medicine, Chelsea Bridge Road, London SW1W 8RH
L. H. Collier
Affiliation:
Medical Research Council Trachoma Unit, MRC Laboratories, Fajara, The Gambia and The Lister Institute of Preventive Medicine, Chelsea Bridge Road, London SW1W 8RH
Shiona Sowa
Affiliation:
Medical Research Council Trachoma Unit, MRC Laboratories, Fajara, The Gambia and The Lister Institute of Preventive Medicine, Chelsea Bridge Road, London SW1W 8RH
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Summary

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Of 60 TRIC agents isolated from Gambian children with trachoma, 25 were serotype 1 and the remainder type 2. There was a pronounced difference in the proportions of these types in the two villages studied. In the village with a predominance of type 2 strains, TRIC agents remained confined to 2 adjacent compounds over a 14 month observation period. All 19 type 1 strains examined were characterized by the appearance in yolk sac smears of compact aggregates of elementary bodies; such aggregates were seen in only 2 of 35 type 2 strains, and may reflect a chemical difference in the surface of the elementary bodies or in a substance elaborated during their replication.

Type
Research Article
Information
Journal of Hygiene , Volume 72 , Issue 3 , June 1974 , pp. 389 - 395
Copyright
Copyright © Cambridge University Press 1974

References

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