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Clinical Characteristics of the First 100 Patients of COVID-19 in Tobruk, Libya: A Brief Report From Low-Resource Settings

Published online by Cambridge University Press:  19 April 2021

Faisal Ismail*
Affiliation:
Clinical Laboratory Department, Faculty of Medical Technology, University of Tobruk, Tobruk, Libya National Centre for Disease Control, Tobruk, Libya
Atiya Farag
Affiliation:
National Centre for Disease Control, Tobruk, Libya
Soghra Haq
Affiliation:
Clinical Laboratory Department, Faculty of Medical Technology, University of Tobruk, Tobruk, Libya
Mohammad A. Kamal
Affiliation:
West China School of Nursing/Institutes for Systems Genetics, Frontiers Science Centre for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, Sichuan, China King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, Saudi Arabia Enzymoics, Novel Global Community Educational Foundation, Australia
*
Corresponding author: Faisal Ismail, Email: [email protected].

Abstract

Objective:

This study aims to report the clinical features of a cohort of patients with suspected coronavirus disease (COVID-19) from Tobruk, Libya, and reflect upon the diagnosis challenge in low-resource settings.

Methods:

A descriptive report of the first 100 patients with suspected COVID-19 who have visited the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 screening clinic at the National Centre for Disease Control in Tobruk, Libya.

Results:

The most common presenting symptoms were fever (90%), cough (89%), dyspnea (85%), sore throat (79%), fatigue (78%), headache (64%), loss of smell (52%), loss of taste (53%), loss of appetite (43%), nausea and vomiting (26%), diarrhea (22%), and rhinorrhea (16%); 51% of the patients had lymphocytopenia, whereas 13% had thrombocytopenia. Bilateral infiltrates were the most common radiologic finding on chest X-ray (76%), and COVID-19 IgM and/or IgG antibodies were detected in 80% of the patients, whereas only 37% of the patients were tested positive by the reverse transcriptase polymerase chain reaction (RT-PCR).

Conclusions:

The disease continued its spread across the region. Fever, cough, and dyspnea were the main symptoms; 21% of the patients did not have any chest X-ray abnormalities. Initial negative results for either antibody testing or RT-PCR-testing for COVID-19 do not rule out the infection.

Type
Brief Report
Copyright
© Society for Disaster Medicine and Public Health, Inc. 2021

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References

Cucinotta, D, Vanelli, M. WHO declares COVID-19 a pandemic. Acta Biomed. 2020;91(1):157-160.Google ScholarPubMed
The National Centre of Disease Control of Libya. Country situation of COVID-19. 2006-2021. https://ncdc.org.ly/Ar/situation-of-corona/. Accessed February 18, 2021.Google Scholar
Guan, W-J, Ni, Z-Y, Hu, Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708-1720.CrossRefGoogle ScholarPubMed
Goyal, P, Choi, JJ, Pinheiro, LC, et al. Clinical characteristics of COVID-19 in New York City. N Engl J Med. 2020;382(24):2372-2374.CrossRefGoogle ScholarPubMed
Sethuraman, N, Jeremiah, SS, Ryo, A. Interpreting diagnostic tests for SARS-CoV-2. JAMA. 2020;323(22):2249-2251.CrossRefGoogle ScholarPubMed
Riccò, M, Ferraro, P, Gualerzi, G, et al. Point-of-care diagnostic tests for detecting SARS-CoV-2 antibodies: a systematic review and meta-analysis of real-world data. J Clin Med. 2020;9(5):1515.CrossRefGoogle ScholarPubMed
Kucirka, LM, Lauer, SA, Laeyendecker, O, et al. Variation in false-negative rate of reverse transcriptase polymerase chain reaction–based SARS-CoV-2 tests by time since exposure. Ann Intern Med. 2020;173(4):262-267.CrossRefGoogle ScholarPubMed
Wong, HYF, Lam, HYS, Fong, AH. Frequency and distribution of chest radiographic findings in patients positive for COVID-19. 2020;296(2):E72-E78.Google Scholar
Ai, T, Yang, Z, Hou, H, et al. Correlation of chest CT and RT-PCR testing for coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology. 2020;296(2):E32-E40.CrossRefGoogle Scholar
Elshazli, RM, Toraih, EA, Elgaml, A, et al. Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: a meta-analysis of 6320 patients. PLoS One. 2020;15(8):e0238160.CrossRefGoogle ScholarPubMed