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Familial trichotillomania: role of genetic factors in the determination of subtypes

Published online by Cambridge University Press:  11 March 2013

Ghaffari Nejad Alireza ,
Fariborz Estilaee  and
Mohammad M. Sadeghi
Ghaffari Nejad Alireza
Affiliation:
Psychiatry Department, Beheshti Hospital, Kerman University of Medical Sciences and Health Services, Kerman, Iran
Fariborz Estilaee*
Affiliation:
Psychiatry Department, Beheshti Hospital, Kerman University of Medical Sciences and Health Services, Kerman, Iran
Mohammad M. Sadeghi
Affiliation:
Psychiatry Department, Beheshti Hospital, Kerman University of Medical Sciences and Health Services, Kerman, Iran
*
Fariborz Estilaee, Resident of Psychiatry, Psychiatry Department, Beheshti Hospital, Kerman University of Medical Sciences and Health Services, Kerman, Iran. Tel: +98 341 2116328; Fax: +98 341 2110856; E-mail: [email protected]
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Abstract

Objectives

Trichotillomania (TTM) is a psychiatric syndrome characterised by the inability to control repetitive hair pulling. Psychiatric data reveal that TTM is not usually prevalent among all family members of patients, and so far only one case of familial TTM has been reported.

Methods

In this study, we report a case of familial TTM that afflicted four sisters and discuss the importance of genetic factors in this disorder.

Results

This report suggests that, similar to many other psychiatric disorders, TTM can be detected in other family members and that genetic factors not only have a significant role in the development of such disorders but also in determination of the disorder subtype. This report also shows that the comorbidities in one member of the family might predict the existence of comorbidities in other members. On the basis of response to medication.

Conclusion

the authors suggest that a genetic disorder like polymorphism in serotonin receptors or dopamine can cause such a disorder.

Keywords

trichotillomaniageneticfamilialsubtype
Type
Case Report
Information
Acta Neuropsychiatrica , Volume 25 , Issue 3 , June 2013 , pp. 187 - 190
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 2013 

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