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Chapter 5 - The Pathology of Lung Transplantation

Published online by Cambridge University Press:  17 March 2018

Phillip Ruiz
Affiliation:
University of Miami School of Medicine
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Publisher: Cambridge University Press
Print publication year: 2018

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References

Hardy, JD, Webb, WR, Dalton, ML Jr., Walker, GR Jr. Lung Homotransplantation in Man: Report of the Initial Case. JAMA. 1963 Dec 21;186(12):1065–74.Google Scholar
Cooper, JD, Billingham, M, Egan, T, Hertz, MI, Higenbottam, T, Lynch, J, et al. A Working Formulation for the Standardization of Nomenclature and for Clinical Staging of Chronic Dysfunction in Lung Allografts. International Society for Heart and Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 1993 Oct;12(5):713–6.Google Scholar
Veith, FJ, Hagstrom, JW. Alveolar Manifestations of Rejection: An Important Cause of the Poor Results with Human Lung Transplantation. Ann Surg. 1972 Mar;175(3):336–48.Google Scholar
Veith, FJ, Kamholz, SL, Mollenkopf, FP, Montefusco, CM. Lung Transplantation 1983. Transplantation. 1983 Apr;35(4):271–8.Google Scholar
Reitz, BA, Wallwork, JL, Hunt, SA, Pennock, JL, Billingham, ME, Oyer, PE, et al. Heart-Lung Transplantation: Successful Therapy for Patients with Pulmonary Vascular Disease. N Engl J Med. 1982 Mar 11;306(10):557–64.Google Scholar
Mallidi, HR. Lung Transplantation. Tex Heart Inst J. 2012;39(6):852–3.Google Scholar
Christie, JD, Edwards, LB, Kucheryavaya, AY, Benden, C, Dipchand, AI, Dobbels, F, et al. The Registry of the International Society for Heart and Lung Transplantation: 29th Adult Lung and Heart-Lung Transplant Report-2012. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2012 Oct;31(10):1073–86.Google Scholar
Benden, C, Edwards, LB, Kucheryavaya, AY, Christie, JD, Dipchand, AI, Dobbels, F, et al. The Registry of the International Society for Heart and Lung Transplantation: Fifteenth Pediatric Lung and Heart-Lung Transplantation Report–2012. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2012 Oct;31(10):1087–95.Google Scholar
Kotloff, RM, Thabut, G. Lung Transplantation. Am J Respir Crit Care Med. 2011 Jul 15;184(2):159–71.Google Scholar
Kotsimbos, T, Williams, TJ, Anderson, GP. Update on Lung Transplantation: Programmes, Patients and Prospects. Eur Respir Rev Off J Eur Respir Soc. 2012 Dec 1;21(126):271305.Google Scholar
Decramer, M, Janssens, W, Miravitlles, M. Chronic Obstructive Pulmonary Disease. Lancet. 2012 Apr 7;379(9823):1341–51.Google Scholar
Singer, JP, Yusen, RD. Defining Patient-reported Outcomes in Chronic Obstructive Pulmonary Disease: The Patient-centered Experience. Med Clin North Am. 2012 Jul;96(4):767–87.Google Scholar
Egan, TM, Murray, S, Bustami, RT, Shearon, TH, McCullough, KP, Edwards, LB, et al. Development of the New Lung Allocation System in the United States. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2006;6(5 Pt 2):1212–27.Google Scholar
Kotloff, RM. Risk Stratification of Lung Transplant Candidates: Implications for Organ Allocation. Ann Intern Med. 2013 May 7;158(9):699700.Google Scholar
Snell, GI, Paraskeva, M, Westall, GP. Donor Selection and Management. Semin Respir Crit Care Med. 2013 Jun;34(3):361–70.Google Scholar
Snell, GI, Westall, GP. Selection and Management of the Lung Donor. Clin Chest Med. 2011 Jun;32(2):223–32.CrossRefGoogle ScholarPubMed
Griffin, SM, Robertson, AGN, Bredenoord, AJ, Brownlee, IA, Stovold, R, Brodlie, M, et al. Aspiration and Allograft Injury Secondary to Gastroesophageal Reflux Occur in the Immediate Post-lung Transplantation Period (Prospective Clinical Trial). Ann Surg. 2013 Nov;258(5):705–12.Google Scholar
Reyes, KG, Mason, DP, Thuita, L, Nowicki, ER, Murthy, SC, Pettersson, GB, et al. Guidelines for Donor Lung Selection: Time for Revision? Ann Thorac Surg. 2010 Jun;89(6):17561764; discussion 1764–1765.CrossRefGoogle ScholarPubMed
Medeiros, IL, Pêgo-Fernandes, PM, Mariani, AW, Fernandes, FG, do Vale Unterpertinger, F, Canzian, M, et al. Histologic and Functional Evaluation of Lungs Reconditioned by ex Vivo Lung Perfusion. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2012 Mar;31(3):305–9.Google Scholar
Ingemansson, R, Eyjolfsson, A, Mared, L, Pierre, L, Algotsson, L, Ekmehag, B, et al. Clinical Transplantation of Initially Rejected Donor Lungs after Reconditioning ex Vivo. Ann Thorac Surg. 2009 Jan;87(1):255–60.Google Scholar
Belli, EV, Landolfo, K, Keller, C, Thomas, M, Odell, J. Lung Cancer Following Lung Transplant: Single Institution 10 Year Experience. Lung Cancer Amst Neth. 2013 Sep;81(3):451–4.Google Scholar
Strollo, DC, Dacic, S, Ocak, I, Pilewski, J, Bermudez, C, Crespo, MM. Malignancies Incidentally Detected at Lung Transplantation: Radiologic and Pathologic Features. AJR Am J Roentgenol. 2013 Jul;201(1):108–16.CrossRefGoogle ScholarPubMed
Lee, JC, Christie, JD. Primary Graft Dysfunction. Clin Chest Med. 2011 Jun;32(2):279–93.Google Scholar
Lee, JC, Christie, JD. Primary Graft Dysfunction. Proc Am Thorac Soc. 2009 Jan 15;6(1):3946.Google Scholar
Suzuki, Y, Cantu, E, Christie, JD. Primary Graft Dysfunction. Semin Respir Crit Care Med. 2013 Jun;34(3):305–19.Google Scholar
Barr, ML, Schenkel, FA, Bowdish, ME, Starnes, VA. Living Donor Lobar Lung Transplantation: Current Status and Future Directions. Transplant Proc. 2005 Nov;37(9):3983–6.Google Scholar
Fiser, SM, Tribble, CG, Long, SM, Kaza, AK, Cope, JT, Laubach, VE, et al. Lung Transplant Reperfusion Injury Involves Pulmonary Macrophages and Circulating Leukocytes in a Biphasic Response. J Thorac Cardiovasc Surg. 2001 Jun;121(6):1069–75.Google Scholar
Frost, AE, Jammal, CT, Cagle, PT. Hyperacute Rejection Following Lung Transplantation. CHEST J. 1996 Aug 1;110(2):559–62.CrossRefGoogle ScholarPubMed
Choi, JK, Kearns, J, Palevsky, HI, Montone, KT, Kaiser, LR, Zmijewski, CM, et al. Hyperacute Rejection of a Pulmonary Allograft. Immediate Clinical and Pathologic Findings. Am J Respir Crit Care Med. 1999 Sep;160(3):1015–8.Google Scholar
De Jesus Peixoto Camargo, J, Marcantonio Camargo, S, Marcelo Schio, S, Noguchi Machuca, T, Adélia Perin, F. Hyperacute Rejection after Single Lung Transplantation: A Case Report. Transplant Proc. 2008 Apr;40(3):867–9.Google Scholar
Bittner, HB, Dunitz, J, Hertz, M, Bolman, MR 3rd, Park, SJ. Hyperacute Rejection in Single Lung Transplantation–Case Report of Successful Management by Means of Plasmapheresis and Antithymocyte Globulin Treatment. Transplantation. 2001 Mar 15;71(5):649–51.Google Scholar
Scornik, JC, Zander, DS, Baz, MA, Donnelly, WH, Staples, ED. Susceptibility of Lung Transplants to Preformed Donor-specific HLA Antibodies as Detected by Flow Cytometry. Transplantation. 1999 Nov 27;68(10):1542–6.Google Scholar
Nguyen, BH, Zwets, E, Schroeder, C, Pierson, RN, Azimzadeh, AM. Beyond Antibody-mediated Rejection: Hyperacute Lung Rejection as a Paradigm for Dysregulated Inflammation. Curr Drug Targets Cardiovasc Haematol Disord. 2005 Jun;5(3):255–69.CrossRefGoogle ScholarPubMed
Tait, BD, Süsal, C, Gebel, HM, Nickerson, PW, Zachary, AA, Claas, FHJ, et al. Consensus Guidelines on the Testing and Clinical Management Issues Associated with HLA and Non-HLA Antibodies in Transplantation. Transplantation. 2013 Jan 15;95(1):1947.CrossRefGoogle ScholarPubMed
Porhownik, NR. Airway Complications Post Lung Transplantation. Curr Opin Pulm Med. 2013 Mar;19(2):174–80.Google Scholar
Santacruz, JF, Mehta, AC. Airway Complications and Management after Lung Transplantation: Ischemia, Dehiscence, and Stenosis. Proc Am Thorac Soc. 2009 Jan 15;6(1):7993.CrossRefGoogle ScholarPubMed
Hasegawa, T, Iacono, AT, Yousem, SA. The Anatomic Distribution of Acute Cellular Rejection in the Allograft Lung. Ann Thorac Surg. 2000 May;69(5):1529–31.Google Scholar
Krishnam, MS, Suh, RD, Tomasian, A, Goldin, JG, Lai, C, Brown, K, et al. Postoperative Complications of Lung Transplantation: Radiologic Findings along a Time Continuum. Radiogr Rev Publ Radiol Soc N Am Inc. 2007 Aug;27(4):957–74.Google Scholar
Herrera, JM, McNeil, KD, Higgins, RS, Coulden, RA, Flower, CD, Nashef, SA, et al. Airway Complications after Lung Transplantation: Treatment and Long-term Outcome. Ann Thorac Surg. 2001 Mar; 71(3):989993; discussion 993–994.Google Scholar
Mulligan, MS. Endoscopic Management of Airway Complications after Lung Transplantation. Chest Surg Clin N Am. 2001 Nov;11(4):907–15.Google Scholar
McManigle, W, Pavlisko, EN, Martinu, T. Acute Cellular and Antibody-mediated Allograft Rejection. Semin Respir Crit Care Med. 2013 Jun;34(3):320–35.Google Scholar
Hopkins, PM, Aboyoun, CL, Chhajed, PN, Malouf, MA, Plit, ML, Rainer, SP, et al. Prospective Analysis of 1,235 Transbronchial Lung Biopsies in Lung Transplant Recipients. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2002 Oct;21(10):1062–7.Google Scholar
Christie, JD, Edwards, LB, Kucheryavaya, AY, Benden, C, Dobbels, F, Kirk, R, et al. The Registry of the International Society for Heart and Lung Transplantation: Twenty-eighth Adult Lung and Heart-Lung Transplant Report—2011. J Heart Lung Transplant. 2011;30(10):1104–22.Google Scholar
Trulock, EP, Christie, JD, Edwards, LB, Boucek, MM, Aurora, P, Taylor, DO, et al. Registry of the International Society for Heart and Lung Transplantation: Twenty-fourth Official Adult Lung and Heart–Lung Transplantation Report—2007. J Heart Lung Transplant. 2007;26(8):782–95.Google Scholar
Patel, JK, Kittleson, M, Kobashigawa, JA. Cardiac Allograft Rejection. The Surgeon. 2011;9(3):160–7.Google Scholar
Shetty, S, Adams, DH, Hubscher, SG. Post-transplant Liver Biopsy and the Immune Response: Lessons for the Clinician. Expert Rev Clin Immunol. 2012 Sep;8(7):645+.Google Scholar
Perkins, D, Verma, M, Park, KJ. Advances of Genomic Science and Systems Biology in Renal Transplantation: A Review. Semin Immunopathol. 2011;33(2):211218.Google Scholar
Sharples, LD, McNeil, K, Stewart, S, Wallwork, J. Risk Factors for Bronchiolitis Obliterans: A Systematic Review of Recent Publications. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2002 Feb;21(2):271–81.Google Scholar
Husain, AN, Siddiqui, MT, Holmes, EW, Chandrasekhar, AJ, McCabe, M, Radvany, R, et al. Analysis of Risk Factors for the Development of Bronchiolitis Obliterans Syndrome. Am J Respir Crit Care Med. 1999 Mar;159(3):829–33.CrossRefGoogle ScholarPubMed
Whelan, TPM, Hertz, MI. Allograft Rejection after Lung Transplantation. Clin Chest Med. 2005 Dec;26(4):599612, vi.Google Scholar
Shitrit, D, Izbicki, G, Fink, G, Bendayan, D, Aravot, D, Saute, M, et al. Late Postoperative Pleural Effusion Following Lung Transplantation: Characteristics and Clinical Implications. Eur J Cardio-Thorac Surg Off J Eur Assoc Cardio-Thorac Surg. 2003 Apr;23(4):494–6.Google Scholar
Martinu, T, Chen, D-F, Palmer, SM. Acute Rejection and Humoral Sensitization in Lung Transplant Recipients. Proc Am Thorac Soc. 2009 Jan 15;6(1):5465.Google Scholar
Hopkins, PM, Aboyoun, CL, Chhajed, PN, Malouf, MA, Plit, ML, Rainer, SP, et al. Association of Minimal Rejection in Lung Transplant Recipients with Obliterative Bronchiolitis. Am J Respir Crit Care Med. 2004 Nov 1;170(9):1022–6.Google Scholar
Stewart, S, Fishbein, MC, Snell, GI, Berry, GJ, Boehler, A, Burke, MM, et al. Revision of the 1996 Working Formulation for the Standardization of Nomenclature in the Diagnosis of Lung Rejection. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2007 Dec;26(12):1229–42.Google Scholar
Chakinala, MM, Ritter, J, Gage, BF, Lynch, JP, Aloush, A, Patterson, GA, et al. Yield of Surveillance Bronchoscopy for Acute Rejection and Lymphocytic Bronchitis/Bronchiolitis after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2004 Dec;23(12):1396–404.Google Scholar
Chaparro, C, Maurer, JR, Chamberlain, DW, Todd, TR. Role of Open Lung Biopsy for Diagnosis in Lung Transplant Recipients: Ten-year Experience. Ann Thorac Surg. 1995 Apr;59(4):928–32.Google Scholar
Burdett, CL, Critchley, RJ, Black, F, Barnard, S, Clark, SC, Corris, PA, et al. Invasive Biopsy Is Effective and Useful after Lung Transplant. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2010 Jul;29(7):759–63.Google Scholar
Husain, AN, Siddiqui, MT, Montoya, A, Chandrasekhar, AJ, Garrity, ER. Post-lung Transplant Biopsies: An 8-year Loyola Experience. Mod Pathol Off J U S Can Acad Pathol Inc. 1996 Feb;9(2):126–32.Google Scholar
Marboe, CC. Pathology of Lung Transplantation. Semin Diagn Pathol. 2007 Aug;24(3):188–98.Google Scholar
Sato, M, Hwang, DM, Ohmori-Matsuda, K, Chaparro, C, Waddell, TK, Singer, LG, et al. Revisiting the Pathologic Finding of Diffuse Alveolar Damage after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant [Internet]. 2012 Feb 11 [cited 2012 Feb 25]; available from: www.ncbi.nlm.nih.gov/pubmed/22330935.Google Scholar
Yousem, SA, Berry, GJ, Cagle, PT, Chamberlain, D, Husain, AN, Hruban, RH, et al. Revision of the 1990 Working Formulation for the Classification of Pulmonary Allograft Rejection: Lung Rejection Study Group. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 1996 Jan;15(1 Pt 1):115.Google Scholar
Arcasoy, SM, Berry, G, Marboe, CC, Tazelaar, HD, Zamora, MR, Wolters, HJ, et al. Pathologic Interpretation of Transbronchial Biopsy for Acute Rejection of Lung Allograft Is Highly Variable. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2011 Feb;11(2):320–8.Google Scholar
Stephenson, A, Flint, J, English, J, Vedal, S, Fradet, G, Chittock, D, et al. Interpretation of Transbronchial Lung Biopsies from Lung Transplant Recipients: Inter- and Intraobserver Agreement. Can Respir J J Can Thorac Soc. 2005 Mar;12(2):75–7.Google Scholar
Colombat, M, Groussard, O, Lautrette, A, Thabut, G, Marrash-Chahla, R, Brugière, O, et al. Analysis of the Different Histologic Lesions Observed in Transbronchial Biopsy for the Diagnosis of Acute Rejection. Clinicopathologic Correlations during the First 6 Months after Lung Transplantation. Hum Pathol. 2005 Apr;36(4):387–94.Google Scholar
Bhorade, SM, Husain, AN, Liao, C, Li, LC, Ahya, VN, Baz, MA, et al. Interobserver Variability in Grading Transbronchial Lung Biopsy Specimens after Lung Transplantation. Chest. 2013 Jun;143(6):1717–24.Google Scholar
Chakinala, MM, Ritter, J, Gage, BF, Aloush, AA, Hachem, RH, Lynch, JP, et al. Reliability for Grading Acute Rejection and Airway Inflammation after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2005 Jun;24(6):652–7.Google Scholar
Hunninghake, GW, Gadek, JE, Kawanami, O, Ferrans, VJ, Crystal, RG. Inflammatory and Immune Processes in the Human Lung in Health and Disease: Evaluation by Bronchoalveolar Lavage. Am J Pathol. 1979 Oct;97(1):149206.Google Scholar
Meyer, KC. Bronchoalveolar Lavage as a Diagnostic Tool. Semin Respir Crit Care Med. 2007 Oct;28(5):546–60.Google Scholar
Tiroke, AH, Bewig, B, Haverich, A. Bronchoalveolar Lavage in Lung Transplantation. State of the Art. Clin Transplant. 1999 Apr;13(2):131–57.Google Scholar
Zheng, L, Orsida, B, Whitford, H, Levvey, B, Ward, C, Walters, EH, et al. Longitudinal Comparisons of Lymphocytes and Subtypes between Airway Wall and Bronchoalveolar Lavage after Human Lung Transplantation. Transplantation. 2005 Jul 27;80(2):185–92.Google Scholar
Vos, R, Vanaudenaerde, BM, Verleden, SE, De Vleeschauwer, SI, Willems-Widyastuti, A, Van Raemdonck, DE, et al. Bronchoalveolar Lavage Neutrophilia in Acute Lung Allograft Rejection and Lymphocytic Bronchiolitis. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2010 Nov;29(11):1259–69.Google Scholar
Clelland, C, Higenbottam, T, Stewart, S, Otulana, B, Wreghitt, T, Gray, J, et al. Bronchoalveolar Lavage and Transbronchial Lung Biopsy during Acute Rejection and Infection in Heart-Lung Transplant Patients. Studies of Cell Counts, Lymphocyte Phenotypes, and Expression of HLA-DR and Interleukin-2 Receptor. Am Rev Respir Dis. 1993 Jun;147(6 Pt 1):1386–92.Google Scholar
Tikkanen, J, Lemström, K, Halme, M, Pakkala, S, Taskinen, E, Koskinen, P. Cytological Monitoring of Peripheral Blood, Bronchoalveolar Lavage Fluid, and Transbronchial Biopsy Specimens during Acute Rejection and Cytomegalovirus Infection in Lung and Heart–Lung Allograft Recipients. Clin Transplant. 2001 Apr;15(2):7788.Google Scholar
Wood, KJ. Regulatory T Cells in Transplantation. Transplant Proc. 2011;43(6):2135–6.Google Scholar
Gregson, AL, Hoji, A, Saggar, R, Ross, DJ, Kubak, BM, Jamieson, BD, et al. Bronchoalveolar Immunologic Profile of Acute Human Lung Transplant Allograft Rejection. Transplantation. 2008 Apr;85(7):1056–9.Google Scholar
Slebos, D-J, Postma, DS, Koëter, GH, Van Der Bij, W, Boezen, M, Kauffman, HF. Bronchoalveolar Lavage Fluid Characteristics in Acute and Chronic Lung Transplant Rejection. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2004 May;23(5):532–40.Google Scholar
Montgomery, RA, Cozzi, E, West, LJ, Warren, DS. Humoral Immunity and Antibody-mediated Rejection in Solid Organ Transplantation. Semin Immunol. 2011;23(4):224–34.Google Scholar
Dragun, D, Catar, R, Philippe, A. Non-HLA Antibodies in Solid Organ Transplantation: Recent Concepts and Clinical Relevance. Curr Opin Organ Transplant. 2013 Aug;18(4):430–5.Google Scholar
Tiriveedhi, V, Gautam, B, Sarma, NJ, Askar, M, Budev, M, Aloush, A, et al. Pre-transplant Antibodies to Kα1 Tubulin and Collagen-V in Lung Transplantation: Clinical Correlations. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2013 Aug;32(8):807–14.Google Scholar
Joudeh, A, Saliba, KA, Topping, KA, Sis, B. Pathologic Basis of Antibody-mediated Organ Transplant Rejection: From Pathogenesis to Diagnosis. Curr Opin Organ Transplant. 2013 Aug;18(4):478–85.Google Scholar
Colvin, RB. Dimensions of Antibody-mediated Rejection. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2010 Jul;10(7):1509–10.Google Scholar
Snyder, LD, Wang, Z, Chen, D-F, Reinsmoen, NL, Finlen-Copeland, CA, Davis, WA, et al. Implications for Human Leukocyte Antigen Antibodies after Lung Transplantation: A 10-year Experience in 441 Patients. Chest. 2013 Jul;144(1):226–33.Google Scholar
Takemoto, SK, Zeevi, A, Feng, S, Colvin, RB, Jordan, S, Kobashigawa, J, et al. National Conference to Assess Antibody-mediated Rejection in Solid Organ Transplantation. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2004 Jul;4(7):1033–41.Google Scholar
Girnita, AL, Duquesnoy, R, Yousem, SA, Iacono, AT, Corcoran, TE, Buzoianu, M, et al. HLA-specific Antibodies are Risk Factors for Lymphocytic Bronchiolitis and Chronic Lung Allograft Dysfunction. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2005 Jan;5(1):131–8.Google Scholar
Girnita, AL, McCurry, KR, Zeevi, A. Increased Lung Allograft Failure in Patients with HLA-specific Antibody. Clin Transpl. 2007;231–9.Google Scholar
Astor, TL, Weill, D, Cool, C, Teitelbaum, I, Schwarz, MI, Zamora, MR. Pulmonary Capillaritis in Lung Transplant Recipients: Treatment and Effect on Allograft Function. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2005 Dec;24(12):2091–7.Google Scholar
Magro, CM, Deng, A, Pope-Harman, A, Waldman, WJ, Bernard Collins, A, Adams, PW, et al. Humorally Mediated Posttransplantation Septal Capillary Injury Syndrome as a Common Form of Pulmonary Allograft Rejection: A Hypothesis. Transplantation. 2002 Nov 15;74(9):1273–80.Google Scholar
Magro, CM, Pope Harman, A, Klinger, D, Orosz, C, Adams, P, Waldman, J, et al. Use of C4d as a Diagnostic Adjunct in Lung Allograft Biopsies. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2003 Sep;3(9):1143–54.Google Scholar
Ionescu, DN, Girnita, AL, Zeevi, A, Duquesnoy, R, Pilewski, J, Johnson, B, et al. C4d Deposition in Lung Allografts Is Associated with Circulating Anti-HLA Alloantibody. Transpl Immunol. 2005 Oct;15(1):63–8.Google Scholar
Wallace, WD, Reed, EF, Ross, D, Lassman, CR, Fishbein, MC. C4d Staining of Pulmonary Allograft Biopsies: An Immunoperoxidase Study. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2005 Oct;24(10):1565–70.Google Scholar
Girnita, AL, McCurry, KR, Yousem, SA, Pilewski, J, Zeevi, A. Antibody-mediated Rejection in Lung Transplantation: Case Reports. Clin Transpl. 2006;508–10.Google Scholar
Westall, GP, Snell, GI, McLean, C, Kotsimbos, T, Williams, T, Magro, C. C3d and C4d Deposition Early after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2008 Jul;27(7):722–8.Google Scholar
Astor, TL, Galantowicz, M, Phillips, A, Palafox, J, Baker, P. Pulmonary Capillaritis as a Manifestation of Acute Humoral Allograft Rejection Following Infant Lung Transplantation. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2009 Feb;9(2):409–12.Google Scholar
Morrell, MR, Patterson, GA, Trulock, EP, Hachem, RR. Acute Antibody-mediated Rejection after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2009 Jan;28(1):96100.Google Scholar
Yousem, SA, Zeevi, A. The Histopathology of Lung Allograft Dysfunction Associated with the Development of Donor-specific HLA Alloantibodies. Am J Surg Pathol. 2012 Jul;36(7):987–92.Google Scholar
DeNicola, MM, Weigt, SS, Belperio, JA, Reed, EF, Ross, DJ, Wallace, WD. Pathologic Findings in Lung Allografts with Anti-HLA Antibodies. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2013 Mar;32(3):326–32.Google Scholar
Jacob, EK, De Goey, SR, Gandhi, MJ. Positive Virtual Crossmatch with Negative Flow Crossmatch Results in Two Cases. Transpl Immunol. 2011 Jul;25(1):7781.Google Scholar
Witt, CA, Gaut, JP, Yusen, RD, Byers, DE, Iuppa, JA, Bennett Bain, K, et al. Acute Antibody-mediated Rejection after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2013 Oct;32(10):1034–40.Google Scholar
Girnita, AL, Lee, TM, McCurry, KR, Baldwin, WM, Yousem, SA, Detrick, B, et al. Anti-human Leukocyte Antigen Antibodies, Vascular C4d Deposition and Increased Soluble C4d in Broncho-Alveolar Lavage of Lung Allografts. Transplantation. 2008 Jul;86(2):342–7.Google Scholar
Roberts, JA, Barrios, R, Cagle, PT, Ge, Y, Takei, H, Haque, AK, et al. The Presence of Anti-HLA Donor-specific Antibodies in Lung Allograft Recipients Does Not Correlate with C4d Immunofluorescence in Transbronchial Biopsy Specimens. Arch Pathol Lab Med. 2013 Oct 28;Google Scholar
Berry, G, Burke, M, Andersen, C, Angelini, A, Bruneval, P, Calabrese, F, et al. Pathology of Pulmonary Antibody-mediated Rejection: 2012 Update from the Pathology Council of the ISHLT. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2013 Jan;32(1):1421.Google Scholar
Mengel, M, Sis, B, Haas, M, Colvin, RB, Halloran, PF, Racusen, LC, et al. BANFF 2011 Meeting Report: New Concepts in Antibody-mediated Rejection. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg [Internet]. 2012 Feb 2 [cited 2012 Feb 23]; available from: www.ncbi.nlm.nih.gov/pubmed/22300494.Google Scholar
Miller, GG, Destarac, L, Zeevi, A, Girnita, A, McCurry, K, Iacono, A, et al. Acute Humoral Rejection of Human Lung Allografts and Elevation of C4d in Bronchoalveolar Lavage Fluid. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2004 Aug;4(8):1323–30.Google Scholar
Verleden, SE, Ruttens, D, Vandermeulen, E, van Raemdonck, DE, Vanaudenaerde, BM, Verleden, GM, et al. Elevated Bronchoalveolar Lavage Eosinophilia Correlates with Poor Outcome after Lung Transplantation. Transplantation. 2013 Oct 23.Google Scholar
Weigt, SS, DerHovanessian, A, Wallace, WD, Lynch, JP 3rd, Belperio, JA. Bronchiolitis Obliterans Syndrome: The Achilles’ Heel of Lung Transplantation. Semin Respir Crit Care Med. 2013 Jun;34(3):336–51.Google Scholar
Boehler, A, Estenne, M. Obliterative Bronchiolitis after Lung Transplantation. Curr Opin Pulm Med. 2000 Mar;6(2):133–9.Google Scholar
Woo, MS. Overview of Lung Transplantation. Clin Rev Allergy Immunol. 2008 Dec;35(3):154–63.Google Scholar
Saggar, R, Ross, DJ, Saggar, R, Zisman, DA, Gregson, A, Lynch, JP 3rd, et al. Pulmonary Hypertension Associated with Lung Transplantation Obliterative Bronchiolitis and Vascular Remodeling of the Allograft. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2008 Sep;8(9):1921–30.Google Scholar
Jiang, X, Khan, MA, Tian, W, Beilke, J, Natarajan, R, Kosek, J, et al. Adenovirus-mediated HIF-1α Gene Transfer Promotes Repair of Mouse Airway Allograft Microvasculature and Attenuates Chronic Rejection. J Clin Invest. 2011 Jun;121(6):2336–49.Google Scholar
Langenbach, SY, Zheng, L, McWilliams, T, Levvey, B, Orsida, B, Bailey, M, et al. Airway Vascular Changes after Lung Transplant: Potential Contribution to the Pathophysiology of Bronchiolitis Obliterans Syndrome. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2005 Oct;24(10):1550–6.Google Scholar
Dhillon, GS, Zamora, MR, Roos, JE, Sheahan, D, Sista, RR, Van der Starre, P, et al. Lung Transplant Airway Hypoxia: A Diathesis to Fibrosis? Am J Respir Crit Care Med. 2010 Jul 15;182(2):230–6.Google Scholar
Nicolls, MR, Zamora, MR. Bronchial Blood Supply after Lung Transplantation without Bronchial Artery Revascularization. Curr Opin Organ Transplant. 2010 Oct;15(5):563–7.Google Scholar
Khan, MA, Nicolls, MR. Complement-mediated Microvascular Injury Leads to Chronic Rejection. Adv Exp Med Biol. 2013;734a:233–46.Google Scholar
Luckraz, H, Goddard, M, McNeil, K, Atkinson, C, Sharples, LD, Wallwork, J. Is Obliterative Bronchiolitis in Lung Transplantation Associated with Microvascular Damage to Small Airways? Ann Thorac Surg. 2006 Oct;82(4):1212–8.Google Scholar
Pettersson, GB, Karam, K, Thuita, L, Johnston, DR, McCurry, KR, Kapadia, SR, et al. Comparative Study of Bronchial Artery Revascularization in Lung Transplantation. J Thorac Cardiovasc Surg. 2013 Oct;146(4):894900.e3.CrossRefGoogle ScholarPubMed
Fishman, JA, Rubin, RH. Infection in Organ-transplant Recipients. N Engl J Med. 1998 Jun 11;338(24):1741–51.Google Scholar
Hafkin, J, Blumberg, E. Infections in Lung Transplantation: New Insights. Curr Opin Organ Transplant. 2009 Oct;14(5):483–7.Google Scholar
Burguete, SR, Maselli, DJ, Fernandez, JF, Levine, SM. Lung Transplant Infection. Respirol Carlton Vic. 2013 Jan;18(1):2238.Google Scholar
Witt, CA, Meyers, BF, Hachem, RR. Pulmonary Infections Following Lung Transplantation. Thorac Surg Clin. 2012 Aug;22(3):403–12.Google Scholar
Roux, A, Mourin, G, Fastenackels, S, Almeida, JR, Iglesias, MC, Boyd, A, et al. CMV Driven CD8(+) T-cell Activation Is Associated with Acute Rejection in Lung Transplantation. Clin Immunol Orlando Fla. 2013 Jul;148(1):1626.Google Scholar
Paraskeva, M, Bailey, M, Levvey, BJ, Griffiths, AP, Kotsimbos, TC, Williams, TP, et al. Cytomegalovirus Replication within the Lung Allograft Is Associated with Bronchiolitis Obliterans Syndrome. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2011 Oct;11(10):2190–6.Google Scholar
Mehrad, B, Paciocco, G, Martinez, FJ, Ojo, TC, Iannettoni, MD, Lynch, JP 3rd. Spectrum of Aspergillus Infection in Lung Transplant Recipients: Case Series and Review of the Literature. Chest. 2001 Jan;119(1):169–75.Google Scholar
Chalermskulrat, W, Sood, N, Neuringer, IP, Hecker, TM, Chang, L, Rivera, MP, et al. Non-tuberculous Mycobacteria in End Stage Cystic Fibrosis: Implications for Lung Transplantation. Thorax. 2006 Jun;61(6):507–13.Google Scholar
Vadnerkar, A, Clancy, CJ, Celik, U, Yousem, SA, Mitsani, D, Toyoda, Y, et al. Impact of Mold Infections in Explanted Lungs on Outcomes of Lung Transplantation. Transplantation. 2010 Jan 27;89(2):253–60.Google Scholar
King, CS, Khandhar, S, Burton, N, Shlobin, OA, Ahmad, S, Lefrak, E, et al. Native Lung Complications in Single-lung Transplant Recipients and the Role of Pneumonectomy. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2009 Aug;28(8):851–6.Google Scholar
Luong, M-L, Morrissey, O, Husain, S. Assessment of Infection Risks Prior to Lung Transplantation. Curr Opin Infect Dis. 2010 Dec;23(6):578–83.Google Scholar
Watkins, RR, Lemonovich, TL. Evaluation of Infections in the Lung Transplant Patient. Curr Opin Infect Dis. 2012 Apr;25(2):193–8.Google Scholar
Avery, RK. Infections after Lung Transplantation. Semin Respir Crit Care Med. 2006 Oct;27(5):544–51.Google Scholar
De Perrot, M, Liu, M, Waddell, TK, Keshavjee, S. Ischemia-Reperfusion-Induced Lung Injury. Am J Respir Crit Care Med. 2003 Feb 15;167(4):490511.Google Scholar
Christie, JD, Carby, M, Bag, R, Corris, P, Hertz, M, Weill, D, et al. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part II: Definition. A Consensus Statement of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2005 Oct;24(10):1454–9.Google Scholar
Hosseini-Moghaddam, SM, Husain, S. Fungi and Molds Following Lung Transplantation. Semin Respir Crit Care Med. 2010 Apr;31(2):222–33.Google Scholar
Bhaskaran, A, Hosseini-Moghaddam, SM, Rotstein, C, Husain, S. Mold Infections in Lung Transplant Recipients. Semin Respir Crit Care Med. 2013 Jun;34(3):371–9.Google Scholar
Lease, ED, Zaas, DW. Update on Infectious Complications Following Lung Transplantation. Curr Opin Pulm Med. 2011 May;17(3):206–9.Google Scholar
Wang, EHZ, Partovi, N, Levy, RD, Shapiro, RJ, Yoshida, EM, Greanya, ED. Pneumocystis Pneumonia in Solid Organ Transplant Recipients: Not Yet an Infection of the Past. Transpl Infect Dis Off J Transplant Soc. 2012 Oct;14(5):519–25.Google Scholar
Liu, M, Mallory, GB, Schecter, MG, Worley, S, Arrigain, S, Robertson, J, et al. Long-term Impact of Respiratory Viral Infection after Pediatric Lung Transplantation. Pediatr Transplant. 2010 May;14(3):431–6.Google Scholar
Christie, JD, Edwards, LB, Aurora, P, Dobbels, F, Kirk, R, Rahmel, AO, et al. Registry of the International Society for Heart and Lung Transplantation: Twenty-fifth Official Adult Lung and Heart/Lung Transplantation Report–2008. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2008 Sep;27(9):957–69.Google Scholar
Mitsani, D, Nguyen, MH, Kwak, EJ, Silveira, FP, Vadnerkar, A, Pilewski, J, et al. Cytomegalovirus Disease among Donor-positive/Recipient-negative Lung Transplant Recipients in the Era of Valganciclovir Prophylaxis. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2010 Sep;29(9):1014–20.Google Scholar
Shah, PD, McDyer, JF. Viral Infections in Lung Transplant Recipients. Semin Respir Crit Care Med. 2010 Apr;31(2):243–54.Google Scholar
Uhlin, M, Mattsson, J, Maeurer, M. Update on Viral Infections in Lung Transplantation. Curr Opin Pulm Med. 2012 May;18(3):264–70.Google Scholar
Shalhoub, S, Husain, S. Community-acquired Respiratory Viral Infections in Lung Transplant Recipients. Curr Opin Infect Dis. 2013 Aug;26(4):302–8.Google Scholar
Clark, NM, Lynch, JP 3rd, Sayah, D, Belperio, JA, Fishbein, MC, Weigt, SS. DNA Viral Infections Complicating Lung Transplantation. Semin Respir Crit Care Med. 2013 Jun;34(3):380404.Google Scholar
Patel, N, Snyder, LD, Finlen-Copeland, A, Palmer, SM. Is Prevention the Best Treatment? CMV after Lung Transplantation. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2012 Mar;12(3):539–44.Google Scholar
Gottlieb, J, Schulz, TF, Welte, T, Fuehner, T, Dierich, M, Simon, AR, et al. Community-acquired Respiratory Viral Infections in Lung Transplant Recipients: A Single Season Cohort Study. Transplantation. 2009 May 27;87(10):1530–7.Google Scholar
Garantziotis, S, Howell, DN, McAdams, HP, Davis, RD, Henshaw, NG, Palmer, SM. Influenza Pneumonia in Lung Transplant Recipients: Clinical Features and Association with Bronchiolitis Obliterans Syndrome. Chest. 2001 Apr;119(4):1277–80.Google Scholar
Malouf, MA, Glanville, AR. The Spectrum of Mycobacterial Infection after Lung Transplantation. Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 1):1611–6.Google Scholar
Gilljam, M, Scherstén, H, Silverborn, M, Jönsson, B, Ericsson Hollsing, A. Lung Transplantation in Patients with Cystic Fibrosis and Mycobacterium Abscessus Infection. J Cyst Fibros Off J Eur Cyst Fibros Soc. 2010 Jul;9(4):272–6.Google Scholar
Reams, BD, McAdams, HP, Howell, DN, Steele, MP, Davis, RD, Palmer, SM. Posttransplant Lymphoproliferative Disorder: Incidence, Presentation, and Response to Treatment in Lung Transplant Recipients. Chest. 2003 Oct;124(4):1242–9.Google Scholar
Trulock, EP, Edwards, LB, Taylor, DO, Boucek, MM, Keck, BM, Hertz, MI. Registry of the International Society for Heart and Lung Transplantation: Twenty-second Official Adult Lung and Heart-Lung Transplant Report–2005. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2005 Aug;24(8):956–67.Google Scholar
Evens, AM, Roy, R, Sterrenberg, D, Moll, MZ, Chadburn, A, Gordon, LI. Post-Transplantation Lymphoproliferative Disorders: Diagnosis, Prognosis, and Current Approaches to Therapy. Curr Oncol Rep. 2010 Nov;12(6):383–94.Google Scholar
Shitrit, D, Shitrit, AB-G, Dickman, R, Sahar, G, Saute, M, Kramer, MR. Gastrointestinal Involvement of Posttransplant Lymphoproliferative Disorder in Lung Transplant Recipients: Report of a Case. Dis Colon Rectum. 2005 Nov;48(11):2144–7.Google Scholar
Malouf, MA, Chhajed, PN, Hopkins, P, Plit, M, Turner, J, Glanville, AR. Anti-viral Prophylaxis Reduces the Incidence of Lymphoproliferative Disease in Lung Transplant Recipients. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2002 May;21(5):547–54.Google Scholar
Wheless, SA, Gulley, ML, Raab-Traub, N, McNeillie, P, Neuringer, IP, Ford, HJ, et al. Post-transplantation Lymphoproliferative Disease: Epstein-Barr Virus DNA Levels, HLA-A3, and Survival. Am J Respir Crit Care Med. 2008 Nov 15;178(10):1060–5.Google Scholar
Michelson, P, Watkins, B, Webber, SA, Wadowsky, R, Michaels, MG. Screening for PTLD in Lung and Heart-Lung Transplant Recipients by Measuring EBV DNA Load in Bronchoalveolar Lavage Fluid using Real Time PCR. Pediatr Transplant. 2008 Jun;12(4):464–8.Google Scholar
Paranjothi, S, Yusen, RD, Kraus, MD, Lynch, JP, Patterson, GA, Trulock, EP. Lymphoproliferative Disease after Lung Transplantation: Comparison of Presentation and Outcome of Early and Late Cases. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2001 Oct;20(10):1054–63.Google Scholar
Campo, E, Swerdlow, SH, Harris, NL, Pileri, S, Stein, H, Jaffe, ES. The 2008 WHO Classification of Lymphoid Neoplasms and Beyond: Evolving Concepts and Practical Applications. Blood. 2011 May 12;117(19):5019–32.Google Scholar
Tiede, C, Maecker-Kolhoff, B, Klein, C, Kreipe, H, Hussein, K. Risk Factors and Prognosis in T-cell Posttransplantation Lymphoproliferative Diseases: Reevaluation of 163 Cases. Transplantation. 2013 Feb 15;95(3):479–88.Google Scholar
Rowlings, PA, Curtis, RE, Passweg, JR, Deeg, HJ, Socié, G, Travis, LB, et al. Increased Incidence of Hodgkin’s Disease after Allogeneic Bone Marrow Transplantation. J Clin Oncol Off J Am Soc Clin Oncol. 1999 Oct;17(10):3122–7.Google Scholar
Pitman, SD, Huang, Q, Zuppan, CW, Rowsell, EH, Cao, JD, Berdeja, JG, et al. Hodgkin Lymphoma-like Posttransplant Lymphoproliferative Disorder (HL-like PTLD) Simulates Monomorphic B-cell PTLD both Clinically and Pathologically. Am J Surg Pathol. 2006 Apr;30(4):470–6.Google Scholar
Haydar, AA, Denton, M, West, A, Rees, J, Goldsmith, DJA. Sirolimus-induced Pneumonitis: Three Cases and a Review of the Literature. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg. 2004 Jan;4(1):137–9.Google Scholar
Khalife, WI, Kogoj, P, Kar, B. Sirolimus-induced Alveolar Hemorrhage. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2007 Jun;26(6):652–7.Google Scholar
King-Biggs, MB, Dunitz, JM, Park, SJ, Kay Savik, S, Hertz, MI. Airway Anastomotic Dehiscence Associated with Use of Sirolimus Immediately after Lung Transplantation. Transplantation. 2003 May 15;75(9):1437–43.Google Scholar
Zaas, DW. Update on Medical Complications Involving the Lungs. Curr Opin Organ Transplant. 2009 Oct;14(5):488–93.Google Scholar
Camus, P, Martin, WJ 2nd, Rosenow, EC 3rd. Amiodarone Pulmonary Toxicity. Clin Chest Med. 2004 Mar;25(1):6575.Google Scholar
Diaz-Guzman, E, Mireles-Cabodevila, E, Arrossi, A, Kanne, JP, Budev, M. Amiodarone Pulmonary Toxicity after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2008 Sep;27(9):1059–63.Google Scholar
Gilman, MJ, Wang, KP. Transbronchial Lung Biopsy in Sarcoidosis. An Approach to Determine the Optimal Number of Biopsies. Am Rev Respir Dis. 1980 Nov;122(5):721–4.Google Scholar
Martinez, FJ, Orens, JB, Deeb, M, Brunsting, LA, Flint, A, Lynch, JP 3rd. Recurrence of Sarcoidosis Following Bilateral Allogeneic Lung Transplantation. Chest. 1994 Nov;106(5):1597–9.Google Scholar
Shah, L. Lung Transplantation in Sarcoidosis. Semin Respir Crit Care Med. 2007 Feb;28(1):134–40.Google Scholar
Israel-Biet, D, Valeyre, D. Diagnosis of Pulmonary Sarcoidosis. Curr Opin Pulm Med. 2013 Sep;19(5):510–5.Google Scholar
Orens, JB, Estenne, M, Arcasoy, S, Conte, JV, Corris, P, Egan, JJ, et al. International Guidelines for the Selection of Lung Transplant Candidates: 2006 Update–A Consensus Report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2006 Jul;25(7):745–55.Google Scholar
Arcasoy, SM, Hersh, C, Christie, JD, Zisman, D, Pochettino, A, Rosengard, BR, et al. Bronchogenic Carcinoma Complicating Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2001 Oct;20(10):1044–53.Google Scholar
Machuca, TN, Keshavjee, S. Transplantation for Lung Cancer. Curr Opin Organ Transplant. 2012 Oct;17(5):479–84.Google Scholar
Nine, JS, Yousem, SA, Paradis, IL, Keenan, R, Griffith, BP. Lymphangioleiomyomatosis: Recurrence after Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 1994 Aug;13(4):714–9.Google Scholar
Dauriat, G, Mal, H, Thabut, G, Mornex, J-F, Bertocchi, M, Tronc, F, et al. Lung Transplantation for Pulmonary Langerhans’ Cell Histiocytosis: A Multicenter Analysis. Transplantation. 2006 Mar 15;81(5):746–50.Google Scholar
Lee, C, Suh, RD, Krishnam, MS, Lai, CK, Fishbein, MC, Wallace, WD, et al. Recurrent Pulmonary Capillary Hemangiomatosis after Bilateral Lung Transplantation. J Thorac Imaging. 2010 Aug;25(3):W8992.Google Scholar
Frost, AE, Keller, CA, Brown, RW, Noon, GP, Short, HD, Abraham, JL, et al. Giant Cell Interstitial Pneumonitis. Disease Recurrence in the Transplanted Lung. Am Rev Respir Dis. 1993 Nov;148(5):1401–4.Google Scholar
Albores, J, Seki, A, Fishbein, MC, Abtin, F, Lynch, JP 3rd, Wang, T, et al. A Rare Occurrence of Pulmonary Alveolar Proteinosis after Lung Transplantation. Semin Respir Crit Care Med. 2013 Jun;34(3):431–8.Google Scholar
Izbicki, G, Bairey, O, Shitrit, D, Lahav, J, Kramer, MR. Increased Thromboembolic Events after Lung Transplantation. Chest. 2006 Feb;129(2):412–6.Google Scholar
Kahan, ES, Petersen, G, Gaughan, JP, Criner, GJ. High Incidence of Venous Thromboembolic Events in Lung Transplant Recipients. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2007 Apr;26(4):339–44.Google Scholar
Yegen, HA, Lederer, DJ, Barr, RG, Wilt, JS, Fang, Y, Bagiella, E, et al. Risk Factors for Venous Thromboembolism after Lung Transplantation. Chest. 2007 Aug;132(2):547–53.Google Scholar
Dickson, RP, Davis, RD, Rea, JB, Palmer, SM. High Frequency of Bronchogenic Carcinoma after Single-Lung Transplantation. J Heart Lung Transplant Off Publ Int Soc Heart Transplant. 2006 Nov;25(11):1297–301.Google Scholar
Parada, MT, Sepúlveda, C, Alba, A, Salas, A. Malignancy Development in Lung Transplant Patients. Transplant Proc. 2011 Aug;43(6):2316–7.Google Scholar
Desai, R, Collett, D, Watson, CJ, Johnson, P, Evans, T, Neuberger, J. Cancer Transmission from Organ Donors-Unavoidable but Low Risk. Transplantation. 2012 Dec 27;94(12):1200–7.Google Scholar
Fisichella, PM, Davis, CS, Kovacs, EJ. A Review of the Role of GERD-induced Aspiration after Lung Transplantation. Surg Endosc. 2012 May;26(5):1201–4.Google Scholar

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