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Chapter 24 - Contraceptive Choices for Women with HIV Infection

from Section 2A - Sexual and Reproductive Healthcare: Contraception

Published online by Cambridge University Press:  16 January 2024

Johannes Bitzer
Affiliation:
University Women's Hospital, Basel
Tahir A. Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
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Summary

Women account for more than half of the individuals infected with human immunodeficiency virus (HIV), and at particularly high risk are those aged 15–24 years [1]. In the era of combined antiretroviral treatment (ART), HIV has become a chronic manageable condition, and many more affected women can nowadays re-evaluate their reproductive choices, including childbearing and prevention of pregnancy [2].

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Publisher: Cambridge University Press
Print publication year: 2024

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References

UN Women. Facts and figures: HIV and AIDS. 2018. https://bit.ly/3wGpmsu.Google Scholar
World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: Recommendations for a public health approach. 2nd edition. Geneva: World Health Organization, 2016. www.who.int/hiv/pub/arv/arv-2016/en.Google Scholar
Amin, A. Addressing gender inequalities to improve the sexual and reproductive health and wellbeing of women living with HIV. J Int AIDS Soc. 2015;18(Suppl 5):20302.CrossRefGoogle ScholarPubMed
Sharma, M, Walmsley, SL. Contraceptive options for HIV-positive women: Making evidence-based, patient-centred decisions. HIV Med. 2015;16(6):329–36.CrossRefGoogle ScholarPubMed
Scarsi, KK, Darin, KM, Chappell, CA, Nitz, SM, Lamorde, M. Drug–drug interactions, effectiveness, and safety of hormonal contraceptives in women living with HIV. Drug Saf. 2016;39(11):1053–72.CrossRefGoogle ScholarPubMed
Scarsi, KK, Cramer, YS, Rosenkranz, SL et al. Antiretroviral therapy and vaginally administered contraceptive hormones: A three-arm, pharmacokinetic study. Lancet HIV. 2019;6(9):e601e612.CrossRefGoogle ScholarPubMed
Nanda, K, Stuart, GS, Robinson, J et al. Drug interactions between hormonal contraceptives and antiretrovirals. AIDS. 2017;31(7):917–52.CrossRefGoogle ScholarPubMed
Hel, Z, Stringer, E, Mestecky, J. Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infection. Endocr Rev. 2010;31(1):7997.CrossRefGoogle ScholarPubMed
Morrison, CS, Hofmeyr, GJ, Thomas, KK et al. Effects of depot medroxyprogesterone acetate, copper intrauterine devices, and levonorgestrel implants on early HIV disease progression. AIDS Res Hum Retroviruses. 2020;36(8):632–40.CrossRefGoogle ScholarPubMed
Curtis, KM, Hannaford, PC, Rodriguez, MI et al. Hormonal contraception and HIV acquisition among women: An updated systematic review. BMJ Sex Reprod Health. 2020;46(1):816.CrossRefGoogle ScholarPubMed
Tepper, NK, Curtis, KM, Nanda, K, Jamieson, DJ. Safety of intrauterine devices among women with HIV: A systematic review. Contraception. 2016;94(6):713–24.Google ScholarPubMed
Todd, CS, Jones, HE, Langwenya, N et al. Safety and continued use of the levonorgestrel intrauterine system as compared with the copper intrauterine device among women living with HIV in South Africa: A randomized controlled trial. PLoS Med. 2020;17(5):e1003110.CrossRefGoogle ScholarPubMed
Lutalo, T, Musoke, R, Kong, X et al. Effects of hormonal contraceptive use on HIV acquisition and transmission among HIV-discordant couples. AIDS. 2013;27(Suppl 1):S2734.CrossRefGoogle ScholarPubMed
Heffron, R, Donnell, D, Rees, H et al. Use of hormonal contraceptives and risk of HIV-1 transmission: A prospective cohort study. Lancet Infect Dis. 2012;12(1):1926.CrossRefGoogle ScholarPubMed
Evidence for Contraceptive Options and HIV Outcomes (ECHO) Trial Consortium. HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: A randomised, multicentre, open-label trial. Lancet. 2019;394(10195):303–13.Google Scholar
World Health Organization. Medical eligibility criteria for contraceptive use. 5th edition. Geneva: World Health Organization, 2015.Google Scholar
Patel, RC, Bukusi, EA, Baeten, JM. Current and future contraceptive options for women living with HIV. Expert Opin Pharmacother. 2018;19(1):112.CrossRefGoogle ScholarPubMed
Hannaford, PC, Ti, A, Chipato, T, Curtis, KM. Copper intrauterine device use and HIV acquisition in women: A systematic review. BMJ Sex Reprod Health. 2020;46(1):1725.CrossRefGoogle ScholarPubMed
Majeed, SR, West, S, Ling, KH, Das, M, Kearney, BP. Confirmation of the drug–drug interaction potential between cobicistat-boosted antiretroviral regimens and hormonal contraceptives. Antivir Ther. 2019;24(8):557–66.CrossRefGoogle ScholarPubMed
Agrati, C, Mazzotta, V, Pinnetti, C, Biava, G, Bibas, M. Venous thromboembolism in people living with HIV infection (PWH). Transl Res. 2020;S1931–5244(20):30174–2.Google Scholar
Hsue, PY, Waters, DD. HIV infection and coronary heart disease: Mechanisms and management. Nat Rev Cardiol. 2019;16(12):745–59.CrossRefGoogle ScholarPubMed
Patel, RC, Onono, M, Gandhi, M et al. A retrospective cohort analysis comparing pregnancy rates among HIV-positive women using contraceptives and efavirenzor nevirapine-based antiretroviral therapy in Kenya. Lancet HIV. 2015;2(11):e474e482.CrossRefGoogle Scholar
Elliot, ER, Bisdomini, E, Penchala, SD et al. Pharmacokinetics (PK) of ethinylestradiol/levonorgestrel co-administered with atazanavir/cobicistat. HIV Res Clin Pract. 2019;23:110.Google Scholar
Trezza, C, Ford, SL, Gould, E et al. Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol-containing oral contraceptive in healthy adult women. Br J Clin Pharmacol. 2017;83(7):1499–1505.CrossRefGoogle ScholarPubMed

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