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Chapter 8 - Management of Hypertension in Renal Disease in Pregnancy

from Section 3 - Antenatal Care

Published online by Cambridge University Press:  19 May 2018

Kate Bramham
Affiliation:
King’s College Hospital, London
Matt Hall
Affiliation:
Nottingham University Hospitals
Catherine Nelson-Piercy
Affiliation:
Guys's & St Thomas's NHS Foundation Trust, London
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Print publication year: 2018

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References

K/DOQI clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease. American journal of kidney diseases: The official journal of the National Kidney Foundation. 2004; 43: S1290.Google Scholar
Mailloux, LU, Haley, WE. Hypertension in the ESRD patient: Pathophysiology, therapy, outcomes, and future directions. American journal of kidney diseases: The official journal of the National Kidney Foundation. 1998; 32: 705719.Google Scholar
Ong, KL, Cheung, BM, Man, YB, Lau, CP, Lam, KS. Prevalence, awareness, treatment, and control of hypertension among United States adults 1999–2004. Hypertension. 2007; 49: 6975.CrossRefGoogle ScholarPubMed
Sarafidis, PA, Li, S, Chen, SC, Collins, AJ, Brown, WW, Klag, MJ, Bakris, GL. Hypertension awareness, treatment, and control in chronic kidney disease. The American journal of medicine. 2008; 121: 332340.CrossRefGoogle ScholarPubMed
Van Wijk, BL, Klungel, OH, Heerdink, ER, de Boer, A. Rate and determinants of 10-year persistence with antihypertensive drugs. Journal of hypertension. 2005; 23: 21012107.CrossRefGoogle ScholarPubMed
Sarnak, MJ, Levey, AS, Schoolwerth, AC, Coresh, J, Culleton, B, Hamm, LL, McCullough, PA, Kasiske, BL, Kelepouris, E, Klag, MJ, Parfrey, P, Pfeffer, M, Raij, L, Spinosa, DJ, Wilson, PW. Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation. 2003; 108: 21542169.CrossRefGoogle ScholarPubMed
Vanholder, R, Massy, Z, Argiles, A, Spasovski, G, Verbeke, F, Lameire, N. Chronic kidney disease as cause of cardiovascular morbidity and mortality. Nephrology, dialysis, transplantation: Official publication of the European Dialysis and Transplant Association – European Renal Association. 2005; 20: 10481056.CrossRefGoogle ScholarPubMed
Baigent, C, Burbury, K, Wheeler, D. Premature cardiovascular disease in chronic renal failure. Lancet. 2000; 356: 147152.Google Scholar
Klag, MJ, Whelton, PK, Randall, BL, Neaton, JD, Brancati, FL, Ford, CE, Shulman, NB, Stamler, J. Blood pressure and end-stage renal disease in men. The New England journal of medicine. 1996; 334: 1318.CrossRefGoogle ScholarPubMed
Saftlas, AF, Olson, DR, Franks, AL, Atrash, HK, Pokras, R. Epidemiology of preeclampsia and eclampsia in the United States, 1979–1986. Am J Obstet Gynecol. 1990; 163: 460465.CrossRefGoogle ScholarPubMed
Bateman, BT, Bansil, P, Hernandez-Diaz, S, Mhyre, JM, Callaghan, WM, Kuklina, EV. Prevalence, trends, and outcomes of chronic hypertension: A nationwide sample of delivery admissions. American journal of obstetrics and gynecology. 2012; 206: 134 e18.CrossRefGoogle ScholarPubMed
Knight, MKS, Brocklehurst, P, Neilson, J, Shakespeare, J, Kurinczuk, JJ (eds.) on behalf of MBRRACEUK. 2014. Saving lives, improving mothers’ care – Lessons learned to inform future maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2009–12; 2014.Google Scholar
Bramham, K, Parnell, B, Nelson-Piercy, C, Seed, PT, Poston, L, Chappell, LC. Chronic hypertension and pregnancy outcomes: Systematic review and meta-analysis. Bmj. 2014; 348: g2301.CrossRefGoogle ScholarPubMed
NICE. Hypertension in pregnancy. http://guidanceniceorguk/CG107. 2010.Google Scholar
Day, C, Hewins, P, Hildebrand, S, Sheikh, L, Taylor, G, Kilby, M, Lipkin, G. The role of renal biopsy in women with kidney disease identified in pregnancy. Nephrology, dialysis, transplantation: Official publication of the European Dialysis and Transplant Association – European Renal Association. 2008; 23: 201206.CrossRefGoogle ScholarPubMed
Ferraro, A, Somerset, DA, Lipkin, G, Al-Jayyousi, R, Carr, S, Brunskill, N, Kilby, MD. Pregnancy in women with pre-existing renal disease: Maternal and fetal outcome. Journal of Obstetrics and Gynaecology. 2005; 25: S13.Google Scholar
Tuuli, MG, Rampersad, R, Stamilio, D, Macones, G, Odibo, AO. Perinatal outcomes in women with preeclampsia and superimposed preeclampsia: Do they differ? American journal of obstetrics and gynecology. 2011; 204: 508 e17.CrossRefGoogle ScholarPubMed
Chappell, LC, Enye, S, Seed, P, Briley, AL, Poston, L, Shennan, AH. Adverse perinatal outcomes and risk factors for preeclampsia in women with chronic hypertension: A prospective study. Hypertension. 2008; 51: 10021009.CrossRefGoogle ScholarPubMed
Staff, AC, Benton, SJ, von Dadelszen, P, Roberts, JM, Taylor, RN, Powers, RW, Charnock-Jones, DS, Redman, CW. Redefining preeclampsia using placenta-derived biomarkers. Hypertension. 2013/03/06 ed; 2013.CrossRefGoogle Scholar
Verlohren, S, Galindo, A, Schlembach, D, Zeisler, H, Herraiz, I, Moertl, MG, Pape, J, Dudenhausen, JW, Denk, B, Stepan, H. An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia. Am J Obstet Gynecol. 2010; 202: 161 e1e11.CrossRefGoogle ScholarPubMed
Verlohren, S, Herraiz, I, Lapaire, O, Schlembach, D, Moertl, M, Zeisler, H, Calda, P, Holzgreve, W, Galindo, A, Engels, T, Denk, B, Stepan, H. The sFlt-1/PlGF ratio in different types of hypertensive pregnancy disorders and its prognostic potential in preeclamptic patients. American journal of obstetrics and gynecology. 2012; 206: 58 e18.Google Scholar
Benton, SJ, Hu, Y, Xie, F, Kupfer, K, Lee, SW, Magee, LA, von Dadelszen, P. Angiogenic factors as diagnostic tests for preeclampsia: A performance comparison between two commercial immunoassays. Am J Obstet Gynecol. 2011.CrossRefGoogle Scholar
Chappell, LC, Duckworth, S, Seed, PT, Griffin, M, Myers, J, Mackillop, L, Simpson, N, Waugh, J, Anumba, D, Kenny, LC, Redman, CW, Shennan, AH. Diagnostic accuracy of placental growth factor in women with suspected preeclampsia: A prospective multicenter study. Circulation. 2013; 128: 21212131.Google Scholar
Hund, M, Verhagen-Kamerbeek, W, Reim, M, Messinger, D, van der Does, R, Stepan, H. Influence of the sFlt-1/PlGF ratio on clinical decision-making in women with suspected preeclampsia – the PreOS study protocol. Hypertension in Pregnancy. 2015; 34: 102115.CrossRefGoogle ScholarPubMed
Hund, M, Allegranza, D, Schoedl, M, Dilba, P, Verhagen-Kamerbeek, W, Stepan, H. Multicenter prospective clinical study to evaluate the prediction of short-term outcome in pregnant women with suspected preeclampsia (PROGNOSIS): Study protocol. BMC pregnancy and childbirth. 2014; 14: 324.Google Scholar
Bramham, K, Seed, PT, Lightstone, L, Nelson-Piercy, C, Gill, C, Webster, P, Poston, L, Chappell, LC. Diagnostic and predictive biomarkers for pre-eclampsia in patients with established hypertension and chronic kidney disease. Kidney international. 2016; 89: 874885.CrossRefGoogle ScholarPubMed
Magee, LA, von Dadelszen, P, Rey, E, Ross, S, Asztalos, E, Murphy, KE, Menzies, J, Sanchez, J, Singer, J, Gafni, A, Gruslin, A, Helewa, M, Hutton, E, Lee, SK, Lee, T, Logan, AG, Ganzevoort, W, Welch, R, Thornton, JG, Moutquin, JM. Less-tight versus tight control of hypertension in pregnancy. The New England journal of medicine. 2015; 372: 407417.CrossRefGoogle ScholarPubMed
de Greeff, A, Lorde, I, Wilton, A, Seed, P, Coleman, AJ, Shennan, AH. Calibration accuracy of hospital-based non-invasive blood pressure measuring devices. Journal of human hypertension. 2010; 24: 5863.CrossRefGoogle ScholarPubMed
Perry, IJ, Wilkinson, LS, Shinton, RA, Beevers, DG. Conflicting views on the measurement of blood pressure in pregnancy. British journal of obstetrics and gynaecology. 1991; 98: 241243.Google Scholar
Wen, SW, Kramer, MS, Hoey, J, Hanley, JA, Usher, RH. Terminal digit preference, random error, and bias in routine clinical measurement of blood pressure. Journal of clinical epidemiology. 1993; 46: 11871193.CrossRefGoogle ScholarPubMed
Natarajan, P, Shennan, AH, Penny, J, Halligan, AW, de Swiet, M, Anthony, J. Comparison of auscultatory and oscillometric automated blood pressure monitors in the setting of preeclampsia. Am J Obstet Gynecol. 1999; 181: 12031210.Google Scholar
Hermida, RC, Ayala, DE, Iglesias, M. Circadian rhythm of blood pressure challenges office values as the “gold standard” in the diagnosis of gestational hypertension. Chronobiology international. 2003; 20: 135156.CrossRefGoogle ScholarPubMed
Ross-McGill, H, Hewison, J, Hirst, J, Dowswell, T, Holt, A, Brunskill, P, Thornton, JG. Antenatal home blood pressure monitoring: A pilot randomised controlled trial. BJOG: An international journal of obstetrics and gynaecology. 2000; 107: 217221.CrossRefGoogle ScholarPubMed
James, PA, Oparil, S, Carter, BL, Cushman, WC, Dennison-Himmelfarb, C, Handler, J, Lackland, DT, LeFevre, ML, MacKenzie, TD, Ogedegbe, O, Smith, SC Jr., Svetkey, LP, Taler, SJ, Townsend, RR, Wright, JT Jr., Narva, AS, Ortiz, E. 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). Jama. 2014; 311: 507520.CrossRefGoogle Scholar
Mancia, G, Fagard, R, Narkiewicz, K, Redon, J, Zanchetti, A, Bohm, M, Christiaens, T, Cifkova, R, De Backer, G, Dominiczak, A, Galderisi, M, Grobbee, DE, Jaarsma, T, Kirchhof, P, Kjeldsen, SE, Laurent, S, Manolis, AJ, Nilsson, PM, Ruilope, LM, Schmieder, RE, Sirnes, PA, Sleight, P, Viigimaa, M, Waeber, B, Zannad, F, Burnier, M, Ambrosioni, E, Caufield, M, Coca, A, Olsen, MH, Tsioufis, C, van de Borne, P, Zamorano, JL, Achenbach, S, Baumgartner, H, Bax, JJ, Bueno, H, Dean, V, Deaton, C, Erol, C, Ferrari, R, Hasdai, D, Hoes, AW, Knuuti, J, Kolh, P, Lancellotti, P, Linhart, A, Nihoyannopoulos, P, Piepoli, MF, Ponikowski, P, Tamargo, JL, Tendera, M, Torbicki, A, Wijns, W, Windecker, S, Clement, DL, Gillebert, TC, Rosei, EA, Anker, SD, Bauersachs, J, Hitij, JB, Caulfield, M, De Buyzere, M, De Geest, S, Derumeaux, GA, Erdine, S, Farsang, C, Funck-Brentano, C, Gerc, V, Germano, G, Gielen, S, Haller, H, Jordan, J, Kahan, T, Komajda, M, Lovic, D, Mahrholdt, H, Ostergren, J, Parati, G, Perk, J, Polonia, J, Popescu, BA, Reiner, Z, Ryden, L, Sirenko, Y, Stanton, A, Struijker-Boudier, H, Vlachopoulos, C, Volpe, M, Wood, DA. 2013 ESH/ESC guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). European heart journal. 2013; 34: 21592219.Google Scholar
Klahr, S, Levey, AS, Beck, GJ, Caggiula, AW, Hunsicker, L, Kusek, JW, Striker, G. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease: Modification of Diet in Renal Disease Study Group. The New England journal of medicine. 1994; 330: 877884.CrossRefGoogle ScholarPubMed
Wright, JT Jr., Bakris, G, Greene, T, Agodoa, LY, Appel, LJ, Charleston, J, Cheek, D, Douglas-Baltimore, JG, Gassman, J, Glassock, R, Hebert, L, Jamerson, K, Lewis, J, Phillips, RA, Toto, RD, Middleton, JP, Rostand, SG. Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: Results from the AASK trial. Jama. 2002; 288: 24212431.Google Scholar
Ruggenenti, P, Perna, A, Loriga, G, Ganeva, M, Ene-Iordache, B, Turturro, M, Lesti, M, Perticucci, E, Chakarski, IN, Leonardis, D, Garini, G, Sessa, A, Basile, C, Alpa, M, Scanziani, R, Sorba, G, Zoccali, C, Remuzzi, G. Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): Multicentre, randomised controlled trial. Lancet. 2005; 365: 939946.CrossRefGoogle ScholarPubMed
Arguedas, JA, Perez, MI, Wright, JM. Treatment blood pressure targets for hypertension. The Cochrane database of systematic reviews. 2009; CD004349.CrossRefGoogle Scholar
Upadhyay, A, Earley, A, Haynes, SM, Uhlig, K. Systematic review: Blood pressure target in chronic kidney disease and proteinuria as an effect modifier. Annals of internal medicine. 2011; 154: 541548.CrossRefGoogle ScholarPubMed
Sarnak, MJ, Greene, T, Wang, X, Beck, G, Kusek, JW, Collins, AJ, Levey, AS. The effect of a lower target blood pressure on the progression of kidney disease: Long-term follow-up of the modification of diet in renal disease study. Annals of internal medicine. 2005; 142: 342351.CrossRefGoogle ScholarPubMed
Appel, LJ, Wright, JT Jr., Greene, T, Agodoa, LY, Astor, BC, Bakris, GL, Cleveland, WH, Charleston, J, Contreras, G, Faulkner, ML, Gabbai, FB, Gassman, JJ, Hebert, LA, Jamerson, KA, Kopple, JD, Kusek, JW, Lash, JP, Lea, JP, Lewis, JB, Lipkowitz, MS, Massry, SG, Miller, ER, Norris, K, Phillips, RA, Pogue, VA, Randall, OS, Rostand, SG, Smogorzewski, MJ, Toto, RD, Wang, X. Intensive blood-pressure control in hypertensive chronic kidney disease. The New England journal of medicine. 2010; 363: 918929.CrossRefGoogle ScholarPubMed
Stevens, PE, Levin, A. Evaluation and management of chronic kidney disease: Synopsis of the kidney disease: Improving global outcomes 2012 clinical practice guideline. Annals of internal medicine. 2013; 158: 825830.CrossRefGoogle ScholarPubMed
Zanchetti, A. Blood pressure targets of antihypertensive treatment: Up and down the J-shaped curve. European heart journal. 2010; 31: 28372840.CrossRefGoogle ScholarPubMed
von Dadelszen, P, Ornstein, MP, Bull, SB, Logan, AG, Koren, G, Magee, LA. Fall in mean arterial pressure and fetal growth restriction in pregnancy hypertension: A meta-analysis. Lancet. 2000; 355: 8792.CrossRefGoogle ScholarPubMed
Jafar, TH, Stark, PC, Schmid, CH, Landa, M, Maschio, G, de Jong, PE, de Zeeuw, D, Shahinfar, S, Toto, R, Levey, AS. Progression of chronic kidney disease: The role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: A patient-level meta-analysis. Annals of internal medicine. 2003; 139: 244252.CrossRefGoogle ScholarPubMed
NICE. Hypertension in pregnancy. NICE quality standard 35. www.niceorguk/guidance/qs35/resources/guidance-hypertension-in-pregnancy-pdf. 2013.Google Scholar
Landesman, R, Holze, E, Scherr, L. Fetal mortality in essential hypertension. Obstetrics and gynecology. 1955; 6: 354365.Google ScholarPubMed
Abalos, E, Duley, L, Steyn, DW. Antihypertensive drug therapy for mild to moderate hypertension during pregnancy. The Cochrane database of systematic reviews. 2014; 2: CD002252.Google Scholar
Magee, LA, von Dadelszen, P, Chan, S, Gafni, A, Gruslin, A, Helewa, M, Hewson, S, Kavuma, E, Lee, SK, Logan, AG, McKay, D, Moutquin, JM, Ohlsson, A, Rey, E, Ross, S, Singer, J, Willan, AR, Hannah, ME. The Control of Hypertension in Pregnancy Study pilot trial. BJOG: An international journal of obstetrics and gynaecology. 2007; 114: 770, e1320.Google Scholar
von Dadelszen, P, Magee, LA. Fall in mean arterial pressure and fetal growth restriction in pregnancy hypertension: An updated metaregression analysis. Journal of obstetrics and gynaecology Canada : JOGC = Journal d’obstetrique et gynecologie du Canada : JOGC. 2002; 24: 941945.Google ScholarPubMed
Martin, JN Jr., Thigpen, BD, Moore, RC, Rose, CH, Cushman, J, May, W. Stroke and severe preeclampsia and eclampsia: A paradigm shift focusing on systolic blood pressure. Obstet Gynecol. 2005; 105: 246254.CrossRefGoogle ScholarPubMed
Sibai, BM, Lindheimer, M, Hauth, J, Caritis, S, VanDorsten, P, Klebanoff, M, MacPherson, C, Landon, M, Miodovnik, M, Paul, R, Meis, P, Dombrowski, M. Risk factors for preeclampsia, abruptio placentae, and adverse neonatal outcomes among women with chronic hypertension. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. N Engl J Med. 1998; 339: 667671.CrossRefGoogle ScholarPubMed
Sibai, BM, Mabie, WC, Shamsa, F, Villar, MA, Anderson, GD. A comparison of no medication versus methyldopa or labetalol in chronic hypertension during pregnancy. American journal of obstetrics and gynecology. 1990; 162: 960966; discussion 6–7.CrossRefGoogle ScholarPubMed
Montan, S, Ingemarsson, I, Marsal, K, Sjoberg, NO. Randomised controlled trial of atenolol and pindolol in human pregnancy: Effects on fetal haemodynamics. Bmj. 1992; 304: 946949.CrossRefGoogle ScholarPubMed
Butters, L, Kennedy, S, Rubin, PC. Atenolol in essential hypertension during pregnancy. Bmj. 1990; 301: 587589.CrossRefGoogle ScholarPubMed
Lydakis, C, Lip, GY, Beevers, M, Beevers, DG. Atenolol and fetal growth in pregnancies complicated by hypertension. American journal of hypertension. 1999; 12: 541547.Google Scholar
Redman, CW. Controlled trials of antihypertensive drugs in pregnancy. American journal of kidney diseases: The official journal of the National Kidney Foundation. 1991; 17: 149153.CrossRefGoogle ScholarPubMed
Piper, JM, Ray, WA, Rosa, FW. Pregnancy outcome following exposure to angiotensin-converting enzyme inhibitors. Obstetrics and gynecology. 1992; 80: 429432.Google ScholarPubMed
Velazquez-Armenta, EY, Han, JY, Choi, JS, Yang, KM, Nava-Ocampo, AA. Angiotensin II receptor blockers in pregnancy: A case report and systematic review of the literature. Hypertension in Pregnancy. 2007; 26: 5166.CrossRefGoogle ScholarPubMed
Li, DK, Yang, C, Andrade, S, Tavares, V, Ferber, JR. Maternal exposure to angiotensin converting enzyme inhibitors in the first trimester and risk of malformations in offspring: A retrospective cohort study. Bmj. 2011; 343: d5931.CrossRefGoogle ScholarPubMed
Duley, L, Henderson-Smart, DJ, Meher, S, King, JF. Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev. 2007; CD004659.CrossRefGoogle Scholar
Askie, LM, Duley, L, Henderson-Smart, DJ, Stewart, LA. Antiplatelet agents for prevention of pre-eclampsia: A meta-analysis of individual patient data. Lancet. 2007; 369: 17911798.CrossRefGoogle ScholarPubMed
Bujold, E, Roberge, S, Lacasse, Y, Bureau, M, Audibert, F, Marcoux, S, Forest, JC, Giguere, Y. Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: A meta-analysis. Obstet Gynecol. 2010; 116: 402414.CrossRefGoogle ScholarPubMed
Hofmeyr, GJ, Duley, L, Atallah, A. Dietary calcium supplementation for prevention of pre-eclampsia and related problems: A systematic review and commentary. BJOG: An international journal of obstetrics and gynaecology. 2007; 114: 933943.Google Scholar
McCance, DR, Holmes, VA, Maresh, MJ, Patterson, CC, Walker, JD, Pearson, DW, Young, IS. Vitamins C and E for prevention of pre-eclampsia in women with type 1 diabetes (DAPIT): A randomised placebo-controlled trial. Lancet. 2010; 376: 259266.CrossRefGoogle Scholar
Poston, L, Briley, AL, Seed, PT, Kelly, FJ, Shennan, AH. Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): Randomised placebo-controlled trial. Lancet. 2006; 367: 11451154.CrossRefGoogle ScholarPubMed
Rumbold, AR, Crowther, CA, Haslam, RR, Dekker, GA, Robinson, JS. Vitamins C and E and the risks of preeclampsia and perinatal complications. N Engl J Med. 2006; 354: 17961806.CrossRefGoogle Scholar
Spinnato, JA, 2nd, Freire, S, Pinto, ESJL, Cunha Rudge, MV, Martins-Costa, S, Koch, MA, Goco, N, Santos Cde, B, Cecatti, JG, Costa, R, Ramos, JG, Moss, N, Sibai, BM. Antioxidant therapy to prevent preeclampsia: A randomized controlled trial. Obstet Gynecol. 2007; 110: 13111318.CrossRefGoogle ScholarPubMed
Villar, J, Purwar, M, Merialdi, M, Zavaleta, N, Thi Nhu Ngoc, N, Anthony, J, De Greeff, A, Poston, L, Shennan, A. World Health Organisation multicentre randomised trial of supplementation with vitamins C and E among pregnant women at high risk for pre-eclampsia in populations of low nutritional status from developing countries. BJOG: An international journal of obstetrics and gynaecology. 2009; 116: 780788.CrossRefGoogle Scholar
Cnossen, JS, Morris, RK, ter Riet, G, Mol, BW, van der Post, JA, Coomarasamy, A, Zwinderman, AH, Robson, SC, Bindels, PJ, Kleijnen, J, Khan, KS. Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: A systematic review and bivariable meta-analysis. Cmaj. 2008; 178: 701711.CrossRefGoogle ScholarPubMed
Roncaglia, N, Crippa, I, Locatelli, A, Cameroni, I, Orsenigo, F, Vergani, P, Ghidini, A. Prediction of superimposed preeclampsia using uterine artery Doppler velocimetry in women with chronic hypertension. Prenatal diagnosis. 2008; 28: 710714.CrossRefGoogle ScholarPubMed
Shaker, OG, Shehata, H. Early prediction of preeclampsia in high-risk women. J Womens Health (Larchmt). 2011; 20: 539544.Google Scholar

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