Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-09T08:20:26.870Z Has data issue: false hasContentIssue false

Case 28 - Atypical Pleomorphic Adenoma

Published online by Cambridge University Press:  19 November 2019

By
Alessandro Franchi
Edited by
Alessandro Franchi
Alessandro Franchi
Affiliation:
Università degli Studi di Firenze, Italy
Get access

Summary

The patient was a 50-year-old male who presented with a slowly growing swelling of the left neck. On MRI examination, a 38 × 35 × 25 mm, irregularly shaped lesion, which exhibited low-signal intensity on T1- and T2-weighted images, was detected in the left submandibular gland. No involvement of the regional lymph nodes was present. Left submandibulectomy was performed.

Type
Chapter
Information
Pearls and Pitfalls in Head and Neck Pathology , pp. 60 - 61
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Takeda, Y. An immunohistochemical study of bizarre neoplastic cells in pleomorphic adenoma: its cytological nature and proliferative activity. Pathol Int. 1999;49:993–999.CrossRefGoogle ScholarPubMed
Li, S, Baloch, ZW, Tomaszewski, JE, LiVolsi, VA. Worrisome histologic alterations following fine needle aspiration of benign parotid lesions. Arch Pathol Lab Med. 2000;124:87–91.CrossRefGoogle ScholarPubMed
Papuccuoglu, HU, Lebe, B, Sarioglu, S. Infarction of pleomorphic adenoma: a rare complication of fine needle aspiration obscuring definitive diagnosis. Diagn Cytol. 2001;24:301–303.CrossRefGoogle Scholar
Skalova, A, Michal, M, Ryska, A, Simpson, RH, Kinkor, Z, Walter, J, et al. Oncocytic myoepithelioma and pleomorphic adenoma of the salivary glands. Virchows Arch. 1999;434:537–546.Google ScholarPubMed
Thunnissen, FB, Peterse, JL, Buchholtz, R, Van der Beek, JM, Bosman, FT. Polyploidy in pleomorphic adenomas with cytological atypia. Cytopathology. 1992;3:101–109.CrossRefGoogle ScholarPubMed
Ohtaké, S, Cheng, J, Ida, H, Suzuki, M, Ohshiro, K, Zhang, W, et al. Precancerous foci in pleomorphic adenoma of the salivary gland: recognition of focal carcinoma and atypical tumor cells by P53 immunohistochemistry. J Oral Pathol Med. 2002;31:590–597.CrossRefGoogle ScholarPubMed
Auclair, PL, Ellis, GL. Atypical features in salivary gland mixed tumors: their relationship to malignant transformation. Mod Pathol. 1996 June;9(6):652–657.Google ScholarPubMed
Di Palma, S, Skálová, A, Vanìèek, T, Simpson, RH, Stárek, I, Leivo, I. Non-invasive (intracapsular) carcinoma ex pleomorphic adenoma: recognition of focal carcinoma by HER-2/neu and MIB1 immunohistochemistry. Histopathology. 2005;46:144–152.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure [email protected] is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×