Book contents
- Handbook of Industrial Crystallization
- Handbook of Industrial Crystallization
- Copyright page
- Contents
- Contributors
- Preface to the First Edition
- Preface to the Second Edition
- Preface to the Third Edition
- Chapter 1 Solutions and Solution Properties
- Chapter 2 Crystals and Crystal Growth
- Chapter 3 Crystal Nucleation
- Chapter 4 The Influence of Impurities and Additives on Crystallization
- Chapter 5 Molecular Modeling Applications in Crystallization
- Chapter 6 Crystallization Process Analysis by Population Balance Modeling
- Chapter 7 Selection and Design of Industrial Crystallizers
- Chapter 8 Precipitation Processes
- Chapter 9 Melt Crystallization
- Chapter 10 Crystallizer Mixing
- Chapter 11 Monitoring and Advanced Control of Crystallization Processes
- Chapter 12 Batch Crystallization
- Chapter 13 Crystallization in the Pharmaceutical Industry
- Chapter 14 Crystallization of Proteins
- Chapter 15 Crystallization in Foods
- Chapter 16 Precipitation and Crystallization of Pigments
- Index
- References
Chapter 4 - The Influence of Impurities and Additives on Crystallization
Published online by Cambridge University Press: 14 June 2019
- Handbook of Industrial Crystallization
- Handbook of Industrial Crystallization
- Copyright page
- Contents
- Contributors
- Preface to the First Edition
- Preface to the Second Edition
- Preface to the Third Edition
- Chapter 1 Solutions and Solution Properties
- Chapter 2 Crystals and Crystal Growth
- Chapter 3 Crystal Nucleation
- Chapter 4 The Influence of Impurities and Additives on Crystallization
- Chapter 5 Molecular Modeling Applications in Crystallization
- Chapter 6 Crystallization Process Analysis by Population Balance Modeling
- Chapter 7 Selection and Design of Industrial Crystallizers
- Chapter 8 Precipitation Processes
- Chapter 9 Melt Crystallization
- Chapter 10 Crystallizer Mixing
- Chapter 11 Monitoring and Advanced Control of Crystallization Processes
- Chapter 12 Batch Crystallization
- Chapter 13 Crystallization in the Pharmaceutical Industry
- Chapter 14 Crystallization of Proteins
- Chapter 15 Crystallization in Foods
- Chapter 16 Precipitation and Crystallization of Pigments
- Index
- References
Summary
In previous chapters, the simple case of two-component systems, i.e., one single solute crystallizing in a solvent (or solvent mixture), was mainly considered. However, because crystallization is most often employed as a purification process, numerous impurities resulting from the upstream part of the process are necessarily present in solution, such as buffer components, residual reactants, intermediates, or by-products. These impurities may affect the crystallization process and the resulting crystal properties, even at low concentration. Besides, additives are sometimes placed intentionally in solution with a view to tuning certain crystal properties. The mechanisms by which impurities and additives dissolved in solution affect the crystallization process can be rationalized in a common framework, so they will both be placed under the umbrella of foreign species in this chapter. The species to be purified will instead be referred to as the host species.
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- Information
- Handbook of Industrial Crystallization , pp. 115 - 135Publisher: Cambridge University PressPrint publication year: 2019
References
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