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1 - The evolution of the repertoire and structure of G protein-coupled receptors

from PART I - ADVANCES IN GPCR PROTEIN RESEARCH

Published online by Cambridge University Press:  05 June 2012

By
Torsten Schöneberg ,
Kristin Schröck ,
Claudia Stäubert  and
Andreas Russ
Edited by
Sandra Siehler  and
Graeme Milligan
Torsten Schöneberg
Affiliation:
University of Leipzig
Kristin Schröck
Affiliation:
University of Leipzig
Claudia Stäubert
Affiliation:
University of Leipzig
Andreas Russ
Affiliation:
University of Oxford
Sandra Siehler
Affiliation:
Novartis Institute for Biomedical Research
Graeme Milligan
Affiliation:
University of Glasgow
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Type
Chapter
Information
G Protein-Coupled Receptors
Structure, Signaling, and Physiology
 , pp. 5 - 31
Publisher: Cambridge University Press
Print publication year: 2010

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References

Fredriksson, R., and Schioth, H. B. (2005) Mol Pharmacol 67(5), 1414–1425.CrossRef
Schioth, H. B., and Fredriksson, R. (2005) Gen Comp Endocrinol 142(1–2), 94–101.CrossRef
Akey, J. M., Eberle, M. A., Rieder, M. J., Carlson, C. S., Shriver, M. D., Nickerson, D. A., and Kruglyak, L. (2004) PLoS Biol 2(10), e286.CrossRef
Bustamante, C. D., Fledel-Alon, A., Williamson, S., Nielsen, R., Hubisz, M. T., Glanowski, S., Tanenbaum, D. M., White, T. J., Sninsky, J. J., Hernandez, R. D., Civello, D., Adams, M. D., Cargill, M., and Clark, A. G. (2005) Nature 437(7062), 1153–1157.CrossRef
Nielsen, R., Bustamante, C., Clark, A. G., Glanowski, S., Sackton, T. B., Hubisz, M. J., Fledel-Alon, A., Tanenbaum, D. M., Civello, D., White, T. J. J. S., Adams, M. D., and Cargill, M. (2005) PLoS Biol3(6), e170.
Nielsen, R., Williamson, S., Kim, Y., Hubisz, M. J., Clark, A. G., and Bustamante, C. (2005) Genome Res 15(11), 1566–1575.CrossRef
Sabeti, P. C., Schaffner, S. F., Fry, B., Lohmueller, J., Varilly, P., Shamovsky, O., Palma, A., Mikkelsen, T. S., Altshuler, D., and Lander, E. S. (2006) Science 312(5780), 1614–1620.CrossRef
Sabeti, P. C., Varilly, P., Fry, B., Lohmueller, J., Hostetter, E., Cotsapas, C., Xie, X., Byrne, E. H., McCarroll, S. A., Gaudet, R., Schaffner, S. F., Lander, E. S., Frazer, K. A., Ballinger, D. G., Cox, D. R., Hinds, D. A., Stuve, L. L., Gibbs, R. A., Belmont, J. W., Boudreau, A., Hardenbol, P., Leal, S. M., Pasternak, S., Wheeler, D. A., Willis, T. D., Yu, F., Yang, H., Zeng, C., Gao, Y., Hu, H., Hu, W., Li, C., Lin, W., Liu, S., Pan, H., Tang, X., Wang, J., Wang, W., Yu, J., Zhang, B., Zhang, Q., Zhao, H., Zhao, H., Zhou, J., Gabriel, S. B., Barry, R., Blumenstiel, B., Camargo, A., Defelice, M., Faggart, M., Goyette, M., Gupta, S., Moore, J., Nguyen, H., Onofrio, R. C., Parkin, M., Roy, J., Stahl, E., Winchester, E., Ziaugra, L., Altshuler, D., Shen, Y., Yao, Z., Huang, W., Chu, X., He, Y., Jin, L., Liu, Y., Shen, Y., Sun, W., Wang, H., Wang, Y., Wang, Y., Xiong, X., Xu, L., Waye, M. M., Tsui, S. K., Xue, H., Wong, J. T., Galver, L. M., Fan, J. B., Gunderson, K., Murray, S. S., Oliphant, A. R., Chee, M. S., Montpetit, A., Chagnon, F., Ferretti, V., Leboeuf, M., Olivier, J. F., Phillips, M. S., Roumy, S., Sallee, C., Verner, A., Hudson, T. J., Kwok, P. Y., Cai, D., Koboldt, D. C., Miller, R. D., Pawlikowska, L., Taillon-Miller, P., Xiao, M., Tsui, L. C., Mak, W., Song, Y. Q., Tam, P. K., Nakamura, Y., Kawaguchi, T., Kitamoto, T., Morizono, T., Nagashima, A., Ohnishi, Y., Sekine, A., Tanaka, T., Tsunoda, T., Deloukas, P., Bird, C. P., Delgado, M., Dermitzakis, E. T., Gwilliam, R., Hunt, S., Morrison, J., Powell, D., Stranger, B. E., Whittaker, P., Bentley, D. R., Daly, M. J., Bakker, P. I., Barrett, J., Chretien, Y. R., Maller, J., McCarroll, S., Patterson, N., Pe'er, I., Price, A., Purcell, S., Richter, D. J., Sabeti, P., Saxena, R., Schaffner, S. F., Sham, P. C., Varilly, P., Altshuler, D., Stein, L. D., Krishnan, L., Smith, A. V., Tello-Ruiz, M. K., Thorisson, G. A., Chakravarti, A., Chen, P. E., Cutler, D. J., Kashuk, C. S., Lin, S., Abecasis, G. R., Guan, W., Li, Y., Munro, H. M., Qin, Z. S., Thomas, D. J., McVean, G., Auton, A., Bottolo, L., Cardin, N., Eyheramendy, S., Freeman, C., Marchini, J., Myers, S., Spencer, C., Stephens, M., Donnelly, P., Cardon, L. R., Clarke, G., Evans, D. M., Morris, A. P., Weir, B. S., Tsunoda, T., Johnson, T. A., Mullikin, J. C., Sherry, S. T., Feolo, M., Skol, A., Zhang, H., Zeng, C., Zhao, H., Matsuda, I., Fukushima, Y., Macer, D. R., Suda, E., Rotimi, C. N., Adebamowo, C. A., Ajayi, I., Aniagwu, T., Marshall, P. A., Nkwodimmah, C., Royal, C. D., Leppert, M. F., Dixon, M., Peiffer, A., Qiu, R., Kent, A., Kato, K., Niikawa, N., Adewole, I. F., Knoppers, B. M., Foster, M. W., Clayton, E. W., Watkin, J., Gibbs, R. A., Belmont, J. W., Muzny, D., Nazareth, L., Sodergren, E., Weinstock, G. M., Wheeler, D. A., Yakub, I., Gabriel, S. B., Onofrio, R. C., Richter, D. J., Ziaugra, L., Birren, B. W., Daly, M. J., Altshuler, D., Wilson, R. K., Fulton, L. L., Rogers, J., Burton, J., Carter, N. P., Clee, C. M., Griffiths, M., Jones, M. C., McLay, K., Plumb, R. W., Ross, M. T., Sims, S. K., Willey, D. L., Chen, Z., Han, H., Kang, L., Godbout, M., Wallenburg, J. C., L'Archeveque, P., Bellemare, G., Saeki, K., Wang, H., An, D., Fu, H., Li, Q., Wang, Z., Wang, R., Holden, A. L., Brooks, L. D., McEwen, J. E., Guyer, M. S., Wang, V. O., Peterson, J. L., Shi, M., Spiegel, J., Sung, L. M., Zacharia, L. F., Collins, F. S., Kennedy, K., Jamieson, R., and Stewart, J. (2007) Nature 449(7164), 913–918.CrossRef
Voight, B. F., Kudaravalli, S., Wen, X., and Pritchard, J. K. (2006) PLoS Biol 4(3), e72.CrossRef
Sineshchekov, O. A., Jung, K. H., and Spudich, J. L. (2002) Proc Natl Acad Sci U S A 99(13), 8689–8694.CrossRef
Waschuk, S. A., Bezerra, A. G., Jr., Shi, L., and Brown, L. S. (2005) Proc Natl Acad Sci U S A 102(19), 6879–6883.CrossRef
Soppa, J. (1994) FEBS Lett 342(1), 7–11.CrossRef
Elion, E. A. (2000) Curr Opin Microbiol 3(6), 573–581.CrossRef
Fujisawa, Y., Kato, H., and Iwasaki, Y. (2001) Plant Cell Physiol 42(8), 789–794.CrossRef
Kim, J. Y., Haastert, P. V., and Devreotes, P. N. (1996) Chem Biol 3(4), 239–243.CrossRef
Violin, J. D., and Lefkowitz, R. J. (2007) Trends Pharmacol Sci 28(8), 416–422.CrossRef
Prabhu, Y., and Eichinger, L. (2006) Eur J Cell Biol 85(9–10), 937–946.CrossRef
Taniura, H., Sanada, N., Kuramoto, N., and Yoneda, Y. (2006) J Biol Chem 281(18), 12336–12343.CrossRef
Perovic, S., Krasko, A., Prokic, I., Muller, I. M., and Muller, W. E. (1999) Cell Tissue Res 296(2), 395–404.CrossRef
Pin, J. P., Galvez, T., and Prezeau, L. (2003) Pharmacol Ther 98(3), 325–354.CrossRef
O'Hara, P. J., Sheppard, P. O., Thogersen, H., Venezia, D., Haldeman, B. A., McGrane, V., Houamed, K. M., Thomsen, C., Gilbert, T. L., and Mulvihill, E. R. (1993) Neuron 11(1), 41–52.CrossRef
Kuang, D., Yao, Y., Maclean, D., Wang, M., Hampson, D. R., and Chang, B. S. (2006) Proc Natl Acad Sci U S A 103(38), 14050–14055.CrossRef
Kulkarni, R. D., Thon, M. R., Pan, H., and Dean, R. A. (2005) Genome Biol 6(3), R24.CrossRef
Gookin, T. E., Kim, J., and Assmann, S. M. (2008) Genome Biol 9(7), R120.CrossRef
King, N., Hittinger, C. T., and Carroll, S. B. (2003) Science 301(5631), 361–363.CrossRef
King, N., Westbrook, M. J., Young, S. L., Kuo, A., Abedin, M., Chapman, J., Fairclough, S., Hellsten, U., Isogai, Y., Letunic, I., Marr, M., Pincus, D., Putnam, N., Rokas, A., Wright, K. J., Zuzow, R., Dirks, W., Good, M., Goodstein, D., Lemons, D., Li, W., Lyons, J. B., Morris, A., Nichols, S., Richter, D. J., Salamov, A., Sequencing, J. G., Bork, P., Lim, W. A., Manning, G., Miller, W. T., McGinnis, W., Shapiro, H., Tjian, R., Grigoriev, I. V., and Rokhsar, D. (2008) Nature 451(7180), 783–788.CrossRef
Adell, T., Nefkens, I., and Muller, W. E. (2003) FEBS Lett 554(3), 363–368.CrossRef
Adell, T., Thakur, A. N., and Muller, W. E. (2007) Cell Biol Int 31(9), 939–949.CrossRef
Momose, T., and Houliston, E. (2007) PLoS Biol 5(4), e70.CrossRef
Putnam, N. H., Srivastava, M., Hellsten, U., Dirks, B., Chapman, J., Salamov, A., Terry, A., Shapiro, H., Lindquist, E., Kapitonov, V. V., Jurka, J., Genikhovich, G., Grigoriev, I. V., Lucas, S. M., Steele, R. E., Finnerty, J. R., Technau, U., Martindale, M. Q., and Rokhsar, D. S. (2007) Science 317(5834), 86–94.CrossRef
Srivastava, M., Begovic, E., Chapman, J., Putnam, N. H., Hellsten, U., Kawashima, T., Kuo, A., Mitros, T., Salamov, A., Carpenter, M. L., Signorovitch, A. Y., Moreno, M. A., Kamm, K., Grimwood, J., Schmutz, J., Shapiro, H., Grigoriev, I. V., Buss, L. W., Schierwater, B., Dellaporta, S. L., and Rokhsar, D. S. (2008) Nature 454(7207), 955–960.CrossRefPubMed
Nordstrom, K. J., Lagerstrom, M. C., Waller, L. M., Fredriksson, R., and Schioth, H. B. (2009) Mol Biol Evol 26(1), 71–84.CrossRef
Cardoso, J. C., Pinto, V. C., Vieira, F. A., Clark, M. S., and Power, D. M. (2006) BMC Evol Biol 6, 108.CrossRef
Benton, M. J., and Ayala, F. J. (2003) Science 300(5626), 1698–1700.CrossRef
Feng, D. F., Cho, G., and Doolittle, R. F. (1997) Proc Natl Acad Sci U S A 94(24), 13028–13033.CrossRef
Peterson, K. J., and Butterfield, N. J. (2005) Proc Natl Acad Sci U S A 102(27), 9547–9552.CrossRef
Bouchard, C., Ribeiro, P., Dube, F., and Anctil, M. (2003) J Neurochem 86(5), 1149–1161.CrossRef
Nothacker, H. P., and Grimmelikhuijzen, C. J. (1993) Biochem Biophys Res Commun 197(3), 1062–1069.CrossRef
Saitoh, O., Yuruzume, E., Watanabe, K., and Nakata, H. (1997) Gene 195(1), 55–61.CrossRef
Tierney, A. J. (2001) Comp Biochem Physiol A Mol Integr Physiol 128(4), 791–804.CrossRef
Arendt, D., Tessmar- Raible, K., Snyman, H., Dorresteijn, A. W., and Wittbrodt, J. (2004) Science 306(5697), 869–871.CrossRef
Suga, H., Schmid, V., and Gehring, W. J. (2008) Curr Biol 18(1), 51–55.CrossRef
Alvarez, C. E. (2008) BMC Evol Biol 8, 222.CrossRef
Kamesh, N., Aradhyam, G. K., and Manoj, N. (2008) BMC Evol Biol 8, 129.CrossRef
Hauser, F., Cazzamali, G., Williamson, M., Park, Y., Li, B., Tanaka, Y., Predel, R., Neupert, S., Schachtner, J., Verleyen, P., and Grimmelikhuijzen, C. J. (2008) Front Neuroendocrinol 29(1), 142–165.CrossRef
Gloriam, D. E., Fredriksson, R., and Schioth, H. B. (2007) BMC Genomics 8, 338.CrossRef
Burke, R. D., Angerer, L. M., Elphick, M. R., Humphrey, G. W., Yaguchi, S., Kiyama, T., Liang, S., Mu, X., Agca, C., Klein, W. H., Brandhorst, B. P., Rowe, M., Wilson, K., Churcher, A. M., Taylor, J. S., Chen, N., Murray, G., Wang, D., Mellott, D., Olinski, R., Hallbook, F., and Thorndyke, M. C. (2006) Dev Biol 300(1), 434–460.CrossRef
Lagerstrom, M. C., Hellstrom, A. R., Gloriam, D. E., Larsson, T. P., Schioth, H. B., and Fredriksson, R. (2006) PLoS Comput Biol 2(6), e54.CrossRef
Metpally, R. P., and Sowdhamini, R. (2005) BMC Genomics 6, 106.CrossRef
Vassilatis, D. K., Hohmann, J. G., Zeng, H., Li, F., Ranchalis, J. E., Mortrud, M. T., Brown, A., Rodriguez, S. S., Weller, J. R., Wright, A. C., Bergmann, J. E., and Gaitanaris, G. A. (2003) Proc Natl Acad Sci U S A 100(8), 4903–4908.CrossRef
Dehal, P., and Boore, J. L. (2005) PLoS Biol 3(10), e314.CrossRef
Kuraku, S., Meyer, A., and Kuratani, S. (2009) Mol Biol Evol 26(1), 47–59.CrossRef
Schulz, A., and Schoneberg, T. (2003) J Biol Chem 278(37), 35531–35541.CrossRef
Go, Y., Satta, Y., Takenaka, O., and Takahata, N. (2005) Genetics 170(1), 313–326.CrossRef
Semyonov, J., Park, J. I., Chang, C. L., and Hsu, S. Y. (2008) PLoS ONE 3(4), e1903.CrossRef
Woods, I. G., Wilson, C., Friedlander, B., Chang, P., Reyes, D. K., Nix, R., Kelly, P. D., Chu, F., Postlethwait, J. H., and Talbot, W. S. (2005) Genome Res 15(9), 1307–1314.CrossRef
Noonan, J. P., Grimwood, J., Schmutz, J., Dickson, M., and Myers, R. M. (2004) Genome Res 14(3), 354–366.CrossRef
Ludwig, A., Belfiore, N. M., Pitra, C., Svirsky, V., and Jenneckens, I. (2001) Genetics 158(3), 1203–1215.
Gloriam, D. E., Bjarnadottir, T. K., Yan, Y. L., Postlethwait, J. H., Schioth, H. B., and Fredriksson, R. (2005) Mol Phylogenet Evol 35(2), 470–482.CrossRef
Schöneberg, T., Hermsdorf, T., Engemaier, E., Engel, K., Liebscher, I., Thor, D., Zierau, K., Rö Mpler, H., and Schulz, A. (2007) Purinergic Signal 3, 255–268.CrossRef
Perez, D. M. (2003) Mol Pharmacol 63(6), 1202–1205.CrossRef
Krautwurst, D. (2008) Chem Biodivers 5(6), 842–852.CrossRef
Rouquier, S., and Giorgi, D. (2007) Mutat Res 616(1–2), 95–102.CrossRef
Kratz, E., Dugas, J. C., and Ngai, J. (2002) Trends Genet 18(1), 29–34.CrossRef
Zlotnik, A., Yoshie, O., and Nomiyama, H. (2006) Genome Biol 7(12), 243.CrossRef
Crom, S., Kapsimali, M., Barome, P. O., and Vernier, P. (2003) J Struct Funct Genomics 3(1–4), 161–176.CrossRef
Hashiguchi, Y., and Nishida, M. (2007) Mol Biol Evol 24(9), 2099–2107.CrossRef
Grus, W. E., Shi, P., and Zhang, J. (2007) Mol Biol Evol 24(10), 2153–2157.CrossRef
Nei, M., Niimura, Y., and Nozawa, M. (2008) Nat Rev Genet 9(12), 951–963.CrossRef
Niimura, Y., and Nei, M. (2006) J Hum Genet 51(6), 505–517.CrossRef
Romero, D., and Palacios, R. (1997) Annu Rev Genet 31, 91–111.CrossRef
Cohen, S., Agmon, N., Yacobi, K., Mislovati, M., and Segal, D. (2005) Nucleic Acids Res 33(14), 4519–4526.CrossRef
Rompler, H., Dear, P. H., Krause, J., Meyer, M., Rohland, N., Schoneberg, T., Stiller, M., and Hofreiter, M. (2006) Nature Protocols 1(2), 720–728.CrossRef
Miller, W., Drautz, D. I., Ratan, A., Pusey, B., Qi, J., Lesk, A. M., Tomsho, L. P., Packard, M. D., Zhao, F., Sher, A., Tikhonov, A., Raney, B., Patterson, N., Lindblad-Toh, K., Lander, E. S., Knight, J. R., Irzyk, G. P., Fredrikson, K. M., Harkins, T. T., Sheridan, S., Pringle, T., and Schuster, S. C. (2008) Nature 456(7220), 387–390.CrossRef
Willerslev, E., Cappellini, E., Boomsma, W., Nielsen, R., Hebsgaard, M. B., Brand, T. B., Hofreiter, M., Bunce, M., Poinar, H. N., Dahl- Jensen, D., Johnsen, S., Steffensen, J. P., Bennike, O., Schwenninger, J. L., Nathan, R., Armitage, S., Hoog, C. J., Alfimov, V., Christl, M., Beer, J., Muscheler, R., Barker, J., Sharp, M., Penkman, K. E., Haile, J., Taberlet, P., Gilbert, M. T., Casoli, A., Campani, E., and Collins, M. J. (2007) Science 317(5834), 111–114.CrossRef
Noonan, J. P., Coop, G., Kudaravalli, S., Smith, D., Krause, J., Alessi, J., Chen, F., Platt, D., Paabo, S., Pritchard, J. K., and Rubin, E. M. (2006) Science 314(5802), 1113–1118.CrossRef
Green, R. E., Krause, J., Ptak, S. E., Briggs, A. W., Ronan, M. T., Simons, J. F., Du, L., Egholm, M., Rothberg, J. M., Paunovic, M., and Paabo, S. (2006) Nature 444(7117), 330–336.CrossRef
Balakirev, E. S., and Ayala, F. J. (2003) Annu Rev Genet 37, 123–151.CrossRef
Hurst, L. D. (2002) Trends Genet 18(9), 486.CrossRef
Morgan, K., Conklin, D., Pawson, A. J., Sellar, R., Ott, T. R., and Millar, R. P. (2003) Endocrinology 144(2), 423–436.CrossRef
Rompler, H., Schulz, A., Pitra, C., Coop, G., Przeworski, M., Paabo, S., and Schoneberg, T. (2005) J Biol Chem 280(35), 31068–31075.CrossRef
Rompler, H., Yu, H. T., Arnold, A., Orth, A., and Schoneberg, T. (2006) Genomics 87(6), 724–732.CrossRef
Gaillard, I., Rouquier, S., Chavanieu, A., Mollard, P., and Giorgi, D. (2004) Hum Mol Genet 13(7), 771–780.CrossRef
Torrents, D., Suyama, M., Zdobnov, E., and Bork, P. (2003) Genome Res 13(12), 2559–2567.CrossRef
Wang, X., Grus, W. E., and Zhang, J. (2006) PLoS Biol 4(3), e52.CrossRef
Rompler, H., Staubert, C., Thor, D., Schulz, A., Hofreiter, M., and Schoneberg, T. (2007) Mol Interv 7(1), 17–25.CrossRef
Mombaerts, P. (2001) Annu Rev Genomics Hum Genet 2, 493–510.CrossRef
Young, J. M., and Trask, B. J. (2002) Hum Mol Genet 11(10), 1153–1160.CrossRef
Liman, E. R., and Innan, H. (2003) Proc Natl Acad Sci U S A 100(6), 3328–3332.CrossRef
Zhang, J., and Webb, D. M. (2003) Proc Natl Acad Sci U S A 100(14), 8337–8341.CrossRef
Wang, X., Thomas, S. D., and Zhang, J. (2004) Hum Mol Genet 13(21), 2671–2678.CrossRef
Hoekstra, H. E. (2006) Heredity 97(3), 222–234.CrossRef
Harding, R. M., Healy, E., Ray, A. J., Ellis, N. S., Flanagan, N., Todd, C., Dixon, C., Sajantila, A., Jackson, I. J., Birch-Machin, M. A., and Rees, J. L. (2000) Am J Hum Genet 66(4), 1351–1361.CrossRef
John, P. R., Makova, K., Li, W. H., Jenkins, T., and Ramsay, M. (2003) Ann N Y Acad Sci 994, 299–306.CrossRef
Rees, J. L. (2000) Pigment Cell Res 13(3), 135–140.CrossRef
Gross, J. B., Borowsky, R., and Tabin, C. J. (2009) PLoS Genet 5(1), e1000326.CrossRef
Lalueza-Fox, C., Rompler, H., Caramelli, D., Staubert, C., Catalano, G., Hughes, D., Rohland, N., Pilli, E., Longo, L., Condemi, S., Rasilla, M., Fortea, J., Rosas, A., Stoneking, M., Schoneberg, T., Bertranpetit, J., and Hofreiter, M. (2007) Science 318(5855), 1453–1455.CrossRef
Rompler, H., Rohland, N., Lalueza-Fox, C., Willerslev, E., Kuznetsova, T., Rabeder, G., Bertranpetit, J., Schoneberg, T., and Hofreiter, M. (2006) Science 313(5783), 62.CrossRef
Steiner, C. C., Rompler, H., Boettger, L. M., Schoneberg, T., and Hoekstra, H. E. (2009) Mol Biol Evol 26(1), 35–45.CrossRef
Hoekstra, H. E., Hirschmann, R. J., Bundey, R. A., Insel, P. A., and Crossland, J. P. (2006) Science 313(5783), 101–104.CrossRef
Rosenblum, E. R., Rompler, H., Schoneberg, T., and Hoekstra, H. E. (2009) in press
Kobilka, B., and Schertler, G. F. (2008) Trends Pharmacol Sci 29(2), 79–83.CrossRef
Scheerer, P., Heck, M., Goede, A., Park, J. H., Choe, H. W., Ernst, O. P., Hofmann, K. P., and Hildebrand, P. W. (2009) Proc Natl Acad Sci U S A 106(26), 10660–10665CrossRef
Scheerer, P., Park, J. H., Hildebrand, P. W., Kim, Y. J., Krauss, N., Choe, H. W., Hofmann, K. P., and Ernst, O. P. (2008) Nature 455(7212), 497–502.CrossRef
Park, J. H., Scheerer, P., Hofmann, K. P., Choe, H. W., and Ernst, O. P. (2008) Nature 454(7201), 183–187.CrossRef
Zhang, Y., Devries, M. E., and Skolnick, J. (2006) PLoS Comput Biol 2(2), e13.CrossRef
Baldwin, J. M. (1993) Embo J 12(4), 1693–1703.
Staubert, C., Tarnow, P., Brumm, H., Pitra, C., Gudermann, T., Gruters, A., Schoneberg, T., Biebermann, H., and Rompler, H. (2007) Endocrinology 148(10), 4642–4648.CrossRef
Tarnow, P., Schoneberg, T., Krude, H., Gruters, A., and Biebermann, H. (2003) J Biol Chem 278(49), 48666–48673.CrossRef
Brown, L. S. (2004) Photochem Photobiol Sci 3(6), 555–565.CrossRef
Zhai, Y., Heijne, W. H., Smith, D. W., and Saier, M. H., Jr. (2001) Biochim Biophys Acta 1511(2), 206–223.CrossRef
Taylor, E. W., and Agarwal, A. (1993) FEBS Lett 325(3), 161–166.CrossRef
Pardo, L., Ballesteros, J. A., Osman, R., and Weinstein, H. (1992) Proc Natl Acad Sci U S A 89(9), 4009–4012.CrossRef
Roy, S. W., and Gilbert, W. (2006) Nat Rev Genet 7(3), 211–221.
Bryson-Richardson, R. J., Logan, D. W., Currie, P. D., and Jackson, I. J. (2004) Gene 338(1), 15–23.CrossRefPubMed
Fridmanis, D., Fredriksson, R., Kapa, I., Schioth, H. B., and Klovins, J. (2007) Mol Phylogenet Evol 43(3), 864–880.CrossRef
Venkatesh, B., Ning, Y., and Brenner, S. (1999) Proc Natl Acad Sci U S A 96(18), 10267–10271.CrossRef
Kosugi, S., Ban, T., Akamizu, T., and Kohn, L. D. (1992) Biochem Biophys Res Commun 189(3), 1754–1762.CrossRef
Savarese, T. M., Wang, C. D., and Fraser, C. M. (1992) J Biol Chem 267(16), 11439–11448.
Cook, J. V., and Eidne, K. A. (1997) Endocrinology 138(7), 2800–2806.CrossRef
Gouill, C., Parent, J. L., Rola-Pleszczynski, M., and Stankova, J. (1997) FEBS Lett 402(2–3), 203–208.CrossRef
Perlman, J. H., Wang, W., Nussenzveig, D. R., and Gershengorn, M. C. (1995) J Biol Chem 270(42), 24682–24685.CrossRef
Schulz, A., Grosse, R., Schultz, G., Gudermann, T., and Schoneberg, T. (2000) J Biol Chem 275(4), 2381–2389.CrossRef
Yohannan, S., Faham, S., Yang, D., Whitelegge, J. P., and Bowie, J. U. (2004) Proc Natl Acad Sci U S A 101(4), 959–963.CrossRef
Deville, J., Rey, J., and Chabbert, M. (2009) J Mol Evol 68(5), 475–489.CrossRef
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M., and Miyano, M. (2000) Science 289(5480), 739–745.CrossRef
Tajima, T., Nakae, J., Takekoshi, Y., Takahashi, Y., Yuri, K., Nagashima, T., and Fujieda, K. (1996) Pediatr Res 39(3), 522–526.CrossRef
Gales, C., Kowalski-Chauvel, A., Dufour, M. N., Seva, C., Moroder, L., Pradayrol, L., Vaysse, N., Fourmy, D., and Silvente-Poirot, S. (2000) J Biol Chem 275(23), 17321–17327.CrossRef
McMillan, D. R., Kayes-Wandover, K. M., Richardson, J. A., and White, P. C. (2002) J Biol Chem 277(1), 785–792.CrossRef
Stacey, M., Lin, H. H., Gordon, S., and McKnight, A. J. (2000) Trends Biochem Sci 25(6), 284–289.CrossRef
Kudo, M., Chen, T., Nakabayashi, K., Hsu, S. Y., and Hsueh, A. J. (2000) Mol Endocrinol 14(2), 272–284.CrossRef
Kajava, A. V. (1998) J Mol Biol 277(3), 519–527.CrossRef
Loy, T., Vandersmissen, H. P., Van Hiel, M. B., Poels, J., Verlinden, H., Badisco, L., Vassart, G., and Vanden Broeck, J. (2008) Gen Comp Endocrinol 155(1), 14–21.
Fan, Q. R., and Hendrickson, W. A. (2005) Nature 433(7023), 269–277.CrossRef
Krasnoperov, V. G., Bittner, M. A., Beavis, R., Kuang, Y., Salnikow, K. V., Chepurny, O. G., Little, A. R., Plotnikov, A. N., Wu, D., Holz, R. W., and Petrenko, A. G. (1997) Neuron 18(6), 925–937.CrossRef
Lin, H. H., Chang, G. W., Davies, J. Q., Stacey, M., Harris, J., and Gordon, S. (2004) J Biol Chem 279(30), 31823–31832.CrossRef
Bjarnadottir, T. K., Fredriksson, R., and Schioth, H. B. (2007) Cell Mol Life Sci 64(16), 2104–2119.CrossRef
Kwakkenbos, M. J., Kop, E. N., Stacey, M., Matmati, M., Gordon, S., Lin, H. H., and Hamann, J. (2004) Immunogenetics 55(10), 655–666.
Fredriksson, R., Gloriam, D. E., Hoglund, P. J., Lagerstrom, M. C., and Schioth, H. B. (2003) Biochem Biophys Res Commun 301(3), 725–734.CrossRef
Usui, T., Shima, Y., Shimada, Y., Hirano, S., Burgess, R. W., Schwarz, T. L., Takeichi, M., and Uemura, T. (1999) Cell 98(5), 585–595.CrossRefPubMed
Formstone, C. J., and Little, P. F. (2001) Mech Dev 109(1), 91–94.CrossRef
Hadjantonakis, A. K., Formstone, C. J., and Little, P. F. (1998) Mech Dev 78(1–2), 91–95.CrossRef
Lawrence, P. A., Struhl, G., and Casal, J. (2007) Nat Rev Genet 8(7), 555–563.CrossRef
Strutt, H., and Strutt, D. (2008) Curr Biol 18(20), 1555–1564.CrossRef
Sudhof, T. C. (2001) Annu Rev Neurosci 24, 933–962.CrossRef
Vakonakis, I., Langenhan, T., Promel, S., Russ, A., and Campbell, I. D. (2008) Structure 16(6), 944–953.CrossRefPubMed
Braasch, I., Volff, J. N., and Schartl, M. (2009) Mol Biol Evol 26(4), 783–799.CrossRef
Kesteren, R. E., and Geraerts, W. P. (1998) Ann N Y Acad Sci 839, 25–34.CrossRef
Darlison, M. G., and Richter, D. (1999) Trends Neurosci 22(2), 81–88.CrossRef
Goh, C. S., Bogan, A. A., Joachimiak, M., Walther, D., and Cohen, F. E. (2000) J Mol Biol 299(2), 283–293.CrossRef
Wilkinson, T. N., Speed, T. P., Tregear, G. W., and Bathgate, R. A. (2005) Ann N Y Acad Sci 1041, 534–539.CrossRef
Sudo, S., Kuwabara, Y., Park, J. I., Hsu, S. Y., and Hsueh, A. J. (2005) Endocrinology 146(8), 3596–3604.CrossRef
Costagliola, S., Urizar, E., Mendive, F., and Vassart, G. (2005) Reproduction 130(3), 275–281.CrossRef
Frazer, K. A., Ballinger, D. G., Cox, D. R., Hinds, D. A., Stuve, L. L., Gibbs, R. A., Belmont, J. W., Boudreau, A., Hardenbol, P., Leal, S. M., Pasternak, S., Wheeler, D. A., Willis, T. D., Yu, F., Yang, H., Zeng, C., Gao, Y., Hu, H., Hu, W., Li, C., Lin, W., Liu, S., Pan, H., Tang, X., Wang, J., Wang, W., Yu, J., Zhang, B., Zhang, Q., Zhao, H., Zhao, H., Zhou, J., Gabriel, S. B., Barry, R., Blumenstiel, B., Camargo, A., Defelice, M., Faggart, M., Goyette, M., Gupta, S., Moore, J., Nguyen, H., Onofrio, R. C., Parkin, M., Roy, J., Stahl, E., Winchester, E., Ziaugra, L., Altshuler, D., Shen, Y., Yao, Z., Huang, W., Chu, X., He, Y., Jin, L., Liu, Y., Shen, Y., Sun, W., Wang, H., Wang, Y., Wang, Y., Xiong, X., Xu, L., Waye, M. M., Tsui, S. K., Xue, H., Wong, J. T., Galver, L. M., Fan, J. B., Gunderson, K., Murray, S. S., Oliphant, A. R., Chee, M. S., Montpetit, A., Chagnon, F., Ferretti, V., Leboeuf, M., Olivier, J. F., Phillips, M. S., Roumy, S., Sallee, C., Verner, A., Hudson, T. J., Kwok, P. Y., Cai, D., Koboldt, D. C., Miller, R. D., Pawlikowska, L., Taillon-Miller, P., Xiao, M., Tsui, L. C., Mak, W., Song, Y. Q., Tam, P. K., Nakamura, Y., Kawaguchi, T., Kitamoto, T., Morizono, T., Nagashima, A., Ohnishi, Y., Sekine, A., Tanaka, T., Tsunoda, T., Deloukas, P., Bird, C. P., Delgado, M., Dermitzakis, E. T., Gwilliam, R., Hunt, S., Morrison, J., Powell, D., Stranger, B. E., Whittaker, P., Bentley, D. R., Daly, M. J., Bakker, P. I., Barrett, J., Chretien, Y. R., Maller, J., McCarroll, S., Patterson, N., Pe'er, I., Price, A., Purcell, S., Richter, D. J., Sabeti, P., Saxena, R., Schaffner, S. F., Sham, P. C., Varilly, P., Altshuler, D., Stein, L. D., Krishnan, L., Smith, A. V., Tello-Ruiz, M. K., Thorisson, G. A., Chakravarti, A., Chen, P. E., Cutler, D. J., Kashuk, C. S., Lin, S., Abecasis, G. R., Guan, W., Li, Y., Munro, H. M., Qin, Z. S., Thomas, D. J., McVean, G., Auton, A., Bottolo, L., Cardin, N., Eyheramendy, S., Freeman, C., Marchini, J., Myers, S., Spencer, C., Stephens, M., Donnelly, P., Cardon, L. R., Clarke, G., Evans, D. M., Morris, A. P., Weir, B. S., Tsunoda, T., Mullikin, J. C., Sherry, S. T., Feolo, M., Skol, A., Zhang, H., Zeng, C., Zhao, H., Matsuda, I., Fukushima, Y., Macer, D. R., Suda, E., Rotimi, C. N., Adebamowo, C. A., Ajayi, I., Aniagwu, T., Marshall, P. A., Nkwodimmah, C., Royal, C. D., Leppert, M. F., Dixon, M., Peiffer, A., Qiu, R., Kent, A., Kato, K., Niikawa, N., Adewole, I. F., Knoppers, B. M., Foster, M. W., Clayton, E. W., Watkin, J., Gibbs, R. A., Belmont, J. W., Muzny, D., Nazareth, L., Sodergren, E., Weinstock, G. M., Wheeler, D. A., Yakub, I., Gabriel, S. B., Onofrio, R. C., Richter, D. J., Ziaugra, L., Birren, B. W., Daly, M. J., Altshuler, D., Wilson, R. K., Fulton, L. L., Rogers, J., Burton, J., Carter, N. P., Clee, C. M., Griffiths, M., Jones, M. C., McLay, K., Plumb, R. W., Ross, M. T., Sims, S. K., Willey, D. L., Chen, Z., Han, H., Kang, L., Godbout, M., Wallenburg, J. C., L'Archeveque, P., Bellemare, G., Saeki, K., Wang, H., An, D., Fu, H., Li, Q., Wang, Z., Wang, R., Holden, A. L., Brooks, L. D., McEwen, J. E., Guyer, M. S., Wang, V. O., Peterson, J. L., Shi, M., Spiegel, J., Sung, L. M., Zacharia, L. F., Collins, F. S., Kennedy, K., Jamieson, R., and Stewart, J. (2007) Nature 449(7164), 851–861.CrossRef
Gibbs, R. A., Taylor, J. F., Tassell, C. P., Barendse, W., Eversole, K. A., Gill, C. A., Green, R. D., Hamernik, D. L., Kappes, S. M., Lien, S., Matukumalli, L. K., McEwan, J. C., Nazareth, L. V., Schnabel, R. D., Weinstock, G. M., Wheeler, D. A., Ajmone-Marsan, P., Boettcher, P. J., Caetano, A. R., Garcia, J. F., Hanotte, O., Mariani, P., Skow, L. C., Sonstegard, T. S., Williams, J. L., Diallo, B., Hailemariam, L., Martinez, M. L., Morris, C. A., Silva, L. O., Spelman, R. J., Mulatu, W., Zhao, K., Abbey, C. A., Agaba, M., Araujo, F. R., Bunch, R. J., Burton, J., Gorni, C., Olivier, H., Harrison, B. E., Luff, B., Machado, M. A., Mwakaya, J., Plastow, G., Sim, W., Smith, T., Thomas, M. B., Valentini, A., Williams, P., Womack, J., Woolliams, J. A., Liu, Y., Qin, X., Worley, K. C., Gao, C., Jiang, H., Moore, S. S., Ren, Y., Song, X. Z., Bustamante, C. D., Hernandez, R. D., Muzny, D. M., Patil, S., San Lucas, A., Fu, Q., Kent, M. P., Vega, R., Matukumalli, A., McWilliam, S., Sclep, G., Bryc, K., Choi, J., Gao, H., Grefenstette, J. J., Murdoch, B., Stella, A., Villa-Angulo, R., Wright, M., Aerts, J., Jann, O., Negrini, R., Goddard, M. E., Hayes, B. J., Bradley, D. G., Barbosa da Silva, M., Lau, L. P., Liu, G. E., Lynn, D. J., Panzitta, F., and Dodds, K. G. (2009) Science 324(5926), 528–532.
Liu, X. G., Tan, L. J., Lei, S. F., Liu, Y. J., Shen, H., Wang, L., Yan, H., Guo, Y. F., Xiong, D. H., Chen, X. D., Pan, F., Yang, T. L., Zhang, Y. P., Guo, Y., Tang, N. L., Zhu, X. Z., Deng, H. Y., Levy, S., Recker, R. R., Papasian, C. J., and Deng, H. W. (2009) Am J Hum Genet 84(3), 418–423.CrossRef
Yang, Z. (2007) Mol Biol Evol 24(8), 1586–1591.CrossRef
Yang, Z. (1997) Comput Appl Biosci 13(5), 555–556.
Bamshad, M., and Wooding, S. P. (2003) Nat Rev Genet 4(2), 99–111.CrossRef
Soranzo, N., Bufe, B., Sabeti, P. C., Wilson, J. F., Weale, M. E., Marguerie, R., Meyerhof, W., and Goldstein, D. B. (2005) Curr Biol 15(14), 1257–1265.CrossRef
Coop, G., Pickrell, J. K., Novembre, J., Kudaravalli, S., Li, J., Absher, D., Myers, R. M., Cavalli-Sforza, L. L., Feldman, M. W., and Pritchard, J. K. (2009) PLoS Genet 5(6), e1000500.CrossRef
Hamblin, M. T., and Di Rienzo, A. (2000) Am J Hum Genet 66(5), 1669–1679.CrossRef
Kelley, J. L., Madeoy, J., Calhoun, J. C., Swanson, W., and Akey, J. M. (2006) Genome Res 16(8), 980–989.CrossRef
Liu, Y., Yang, S., Lin, A. A., Cavalli-Sforza, L. L., and Su, B. (2005) J Mol Evol 61(5), 691–696.CrossRef
Maayan, S., Zhang, L., Shinar, E., Ho, J., He, T., Manni, N., Kostrikis, L. G., and Neumann, A. U. (2000) Genes Immun 1(6), 358–361.CrossRef
Novembre, J., Galvani, A. P., and Slatkin, M. (2005) PLoS Biol 3(11), e339.CrossRef
Moreno-Estrada, A., Casals, F., Ramirez- Soriano, A., Oliva, B., Calafell, F., Bertranpetit, J., and Bosch, E. (2008) Mol Biol Evol 25(1), 144–154.CrossRef
Hashiguchi, Y., Furuta, Y., Kawahara, R., and Nishida, M. (2007) Gene 396(1), 170–179.CrossRef
Shi, P., Zhang, J., Yang, H., and Zhang, Y. P. (2003) Mol Biol Evol 20(5), 805–814.CrossRef
Lin, Y. J., Seroude, L., and Benzer, S. (1998) Science 282(5390), 943–946.CrossRef
Schmidt, P. S., Duvernell, D. D., and Eanes, W. F. (2000) Proc Natl Acad Sci U S A 97(20), 10861–10865.CrossRef
Kim, K. S., Reecy, J. M., Hsu, W. H., Anderson, L. L., and Rothschild, M. F. (2004) Domest Anim Endocrinol 26(1), 75–86.CrossRef
Fang, M., Larson, G., Ribeiro, H. S., Li, N., and Andersson, L. (2009) PLoS Genet 5(1), e1000341.CrossRef
Hadley, T. J., and Peiper, S. C. (1997) Blood 89(9), 3077–3091.PubMed
Liberles, S. D., and Buck, L. B. (2006) Nature 442(7103), 645–650.CrossRef
Diaz Arenas, C., and Lehman, N. (2009) Int J Biochem Cell Biol 41(2), 266–273.CrossRef
Joyce, G. F. (2007) Angew Chem Int Ed Engl 46(34), 6420–6436.CrossRef
Ault, A. D., and Broach, J. R. (2006) Protein Eng Des Sel 19(1), 1–8.CrossRef
Coward, P., Wada, H. G., Falk, M. S., Chan, S. D., Meng, F., Akil, H., and Conklin, B. R. (1998) Proc Natl Acad Sci U S A 95(1), 352–357.CrossRef
Pausch, M. H. (1997) Trends Biotechnol 15(12), 487–494.CrossRef
Beukers, M. W., and Ijzerman, A. P. (2005) Trends Pharmacol Sci 26(10), 533–539.CrossRef
Ladds, G., Goddard, A., and Davey, J. (2005) Trends Biotechnol 23(7), 367–373.CrossRef
Armbruster, B. N., Li, X., Pausch, M. H., Herlitze, S., and Roth, B. L. (2007) Proc Natl Acad Sci U S A 104(12), 5163–5168.CrossRef
Conklin, B. R., Hsiao, E. C., Claeysen, S., Dumuis, A., Srinivasan, S., Forsayeth, J. R., Guettier, J. M., Chang, W. C., Pei, Y., McCarthy, K. D., Nissenson, R. A., Wess, J., Bockaert, J., and Roth, B. L. (2008) Nat Methods 5(8), 673–678.CrossRef
Scearce-Levie, K., Coward, P., Redfern, C. H., and Conklin, B. R. (2001) Trends Pharmacol Sci 22(8), 414–420.CrossRef
Baker, J. G., Hall, I. P., and Hill, S. J. (2003) Mol Pharmacol 63(6), 1312–1321.CrossRef
Thor, D., Schulz, A., Hermsdorf, T., and Schoneberg, T. (2008) Biochem J 412(1), 103–112.CrossRef
Arbiza, L., Dopazo, J., and Dopazo, H. (2006) PLoS Comput Biol 2(4), e38.CrossRef
Tang, K., Thornton, K. R., and Stoneking, M. (2007) PLoS Biol 5(7), e171.CrossRef
Williamson, S. H., Hubisz, M. J., Clark, A. G., Payseur, B. A., Bustamante, C. D., and Nielsen, R. (2007) PLoS Genet 3(6), e90.CrossRef
Barreiro, L. B., Laval, G., Quach, H., Patin, E., and Quintana-Murci, L. (2008) Nat Genet 40(3), 340–345.CrossRef

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