Book contents
- Fundamentals of Nanomedicine
- Fundamentals of Nanomedicine
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgments
- 1 The Need for New Perspectives in Medicine
- 2 Nanomedicine: Single-Cell Medicine
- 3 Targeted Drug Delivery
- 4 Drug Delivery Cell Entry Mechanisms
- 5 Nanomaterial Cores for Noninvasive Imaging
- 6 Attaching Biomolecules to Nanoparticles
- 7 Characterizing Nanoparticles
- 8 Nanomedicine Drug Dosing
- 9 Nanodelivery of Therapeutic Genes
- 10 Assessing Nanomedical Therapies at the Single-Cell Level
- 11 Nanotoxicity at the Single-Cell Level
- 12 Designing Nanodelivery Systems for In Vivo Use
- 13 Designing and Testing Nanomedical Devices
- 14 Quality Assurance and Regulatory Issues of Nanomedicine for the Pharmaceutical Industry
- References
- Index
13 - Designing and Testing Nanomedical Devices
Published online by Cambridge University Press: 08 March 2022
Book contents
- Fundamentals of Nanomedicine
- Fundamentals of Nanomedicine
- Copyright page
- Dedication
- Contents
- Preface
- Acknowledgments
- 1 The Need for New Perspectives in Medicine
- 2 Nanomedicine: Single-Cell Medicine
- 3 Targeted Drug Delivery
- 4 Drug Delivery Cell Entry Mechanisms
- 5 Nanomaterial Cores for Noninvasive Imaging
- 6 Attaching Biomolecules to Nanoparticles
- 7 Characterizing Nanoparticles
- 8 Nanomedicine Drug Dosing
- 9 Nanodelivery of Therapeutic Genes
- 10 Assessing Nanomedical Therapies at the Single-Cell Level
- 11 Nanotoxicity at the Single-Cell Level
- 12 Designing Nanodelivery Systems for In Vivo Use
- 13 Designing and Testing Nanomedical Devices
- 14 Quality Assurance and Regulatory Issues of Nanomedicine for the Pharmaceutical Industry
- References
- Index
Summary
“Total design” of nanomedical systems means that you must take a total system-level design approach, but where the order in the design process matters – and each design step affects all preceding and subsequent design steps. The total design concept means that the essence of the design is a multilayered approach corresponding to a multistep targeting and drug delivery process. This chapter teaches how to design integrated nanomedical systems.
Keywords
designing and testing nanomedical devicesintegrated designstotal design conceptautonomous and nonautonomous systemsdifferences between monoclonal and polyclonal antibodiesevaluating targeting to diseased cellsstealth molecules to improve time in circulationintracellular targetingvariables affecting zeta potentialpreventing agglomeration
- Type
- Chapter
- Information
- Fundamentals of Nanomedicine , pp. 255 - 278Publisher: Cambridge University PressPrint publication year: 2022