Book contents
- Fundamentals of Anaesthesia
- Fundamentals of Anaesthesia
- Copyright page
- Dedication
- Contents
- Contributors
- Preface to the first edition
- Preface to the second edition
- Preface to the third edition
- Preface to the fourth edition
- Acknowledgements
- Abbreviations
- Section 1 Clinical anaesthesia
- Section 2 Physiology
- Section 3 Pharmacology
- Chapter 25 Physical chemistry
- Chapter 26 Pharmacodynamics
- Chapter 27 Pharmacokinetics
- Chapter 28 Mechanisms of drug action
- Chapter 29 Anaesthetic gases and vapours
- Chapter 30 Hypnotics and intravenous anaesthetic drugs
- Chapter 31 Analgesic drugs
- Chapter 32 Neuromuscular blocking agents
- Chapter 33 Local anaesthetic agents
- Chapter 34 Central nervous system pharmacology
- Chapter 35 Autonomic nervous system pharmacology
- Chapter 36 Cardiovascular pharmacology
- Chapter 37 Respiratory pharmacology
- Chapter 38 Endocrine pharmacology
- Chapter 39 Gastrointestinal pharmacology
- Chapter 40 Intravenous fluids
- Chapter 41 Pharmacology of haemostasis
- Chapter 42 Antimicrobial therapy
- Chapter 43 Clinical trials and basic statistics
- Section 4 Physics and clinical measurement
- Index
Chapter 35 - Autonomic nervous system pharmacology
from Section 3 - Pharmacology
Published online by Cambridge University Press: 19 January 2017
- Fundamentals of Anaesthesia
- Fundamentals of Anaesthesia
- Copyright page
- Dedication
- Contents
- Contributors
- Preface to the first edition
- Preface to the second edition
- Preface to the third edition
- Preface to the fourth edition
- Acknowledgements
- Abbreviations
- Section 1 Clinical anaesthesia
- Section 2 Physiology
- Section 3 Pharmacology
- Chapter 25 Physical chemistry
- Chapter 26 Pharmacodynamics
- Chapter 27 Pharmacokinetics
- Chapter 28 Mechanisms of drug action
- Chapter 29 Anaesthetic gases and vapours
- Chapter 30 Hypnotics and intravenous anaesthetic drugs
- Chapter 31 Analgesic drugs
- Chapter 32 Neuromuscular blocking agents
- Chapter 33 Local anaesthetic agents
- Chapter 34 Central nervous system pharmacology
- Chapter 35 Autonomic nervous system pharmacology
- Chapter 36 Cardiovascular pharmacology
- Chapter 37 Respiratory pharmacology
- Chapter 38 Endocrine pharmacology
- Chapter 39 Gastrointestinal pharmacology
- Chapter 40 Intravenous fluids
- Chapter 41 Pharmacology of haemostasis
- Chapter 42 Antimicrobial therapy
- Chapter 43 Clinical trials and basic statistics
- Section 4 Physics and clinical measurement
- Index
Summary
The autonomic nervous system (ANS) comprises the sympathetic and parasympathetic nervous systems. Ganglionic synaptic transmission in the ANS is mediated by the release of acetylcholine from the preganglionic neurone. Both muscarinic and nicotinic receptors are involved in mediation of the postganglionic response, as are inhibitory dopaminergic interneurones. In general, sympathetic postganglionic neurones are noradrenergic, and parasympathetic postganglionic neurones are muscarinic (cholinergic). The two systems tend to have opposite actions. Deliberate pharmacological manipulation of the ANS is therefore aimed at sites where physiological or anatomical differences exist between the two systems.
- Type
- Chapter
- Information
- Fundamentals of Anaesthesia , pp. 680 - 694Publisher: Cambridge University PressPrint publication year: 2016