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1 - Drug Research: Between Ethical Demands and Economic Constraints

Published online by Cambridge University Press:  04 December 2009

Michael A. Santoro
Affiliation:
Rutgers University, New Jersey
Jürgen Drews
Affiliation:
Chairman of the Board, Genaissance Pharm. Inc.; Director and Partner, Bear Stearns Health Innoventure Fund LLC
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Summary

Any list of our civilization's achievements in the past would have to include the advances made in medicine. Within the field of medicine, drugs have always played a key role, either directly in the treatment of diseases or indirectly by creating the conditions under which other forms of treatment could be applied. Drug research has been a particularly successful field of activity. However highly it may be regarded in general, this does not mean that there are no grounds for criticism. Some critical questions relating to the code of ethics of drug research will be discussed below.

MEDICAL AND SCIENTIFIC ETHICS

The intellectual and ethical mindsets that have shaped the direction taken by drug research are motivated in two contrasting, yet related, ways: the first one is directed at curing diseases or at least alleviating their symptoms; the second one is scientific in nature and aims at the reliability and reproducibility of the process by which drugs are discovered and developed.

Drug therapy, and hence also drug research, are perceived as part and parcel of the medical – or more specifically of the doctor's – vocation. The declared goal of all drug research has always been to satisfy therapeutic needs. This goal goes hand in hand with the need for effective and safe drugs and for the careful assessment of the risk/benefit relationship in the therapeutic use of drugs, particularly when the relevant side effects of the drugs in question are known.

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Publisher: Cambridge University Press
Print publication year: 2005

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