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17 - Stimulant treatment of adult ADHD

from Section 5 - Pharmacological treatment of adult ADHD

Published online by Cambridge University Press:  04 April 2011

By
Thomas Spencer  and
Joseph Biederman
Edited by
Jan K. Buitelaar ,
Cornelis C. Kan  and
Philip Asherson
Jan K. Buitelaar
Affiliation:
Radboud Universiteit Nijmegen Medical Center
Cornelis C. Kan
Affiliation:
Radboud Universiteit Nijmegen Medical Centerr
Philip Asherson
Affiliation:
Institute of Psychiatry, London
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Summary

Estimates of the prevalence of attention-deficit hyperactivity disorder (ADHD) in adults have been based on a prevalence rate of ADHD children of 5-10% and an estimated persistence rate of 50 to 60% into adulthood, which suggest that ADHD may afflict as many as 2-4% of adults. The authors aim at measuring precisely the degree of therapeutic response and assessing safety and tolerability. The authors show that methylphenidate (MPH) was effective and well tolerated for adults with ADHD in the short term. Osmotic-release oral system (OROS) methylphenidate is a long-acting stimulant demonstrated to be effective in the treatment of children and adolescents with ADHD. Recent work clearly documents that, when therapeutic doses of MPH and amphetamine treatment are used in the treatment of adults with ADHD, they can lead to a robust clinical response that is highly consistent with that observed in pediatric studies using equipotent daily doses.
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Information
ADHD in Adults
Characterization, Diagnosis, and Treatment
 , pp. 191 - 197
Publisher: Cambridge University Press
Print publication year: 2011

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