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26B - Time-Lapse Imaging Should Be a Routine Procedure in Clinical Embryology

Against

from Section IV - Embryology

Published online by Cambridge University Press:  25 November 2021

Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

An evaluation of published data from studies using incubators incorporating time-lapse imaging (TLI) in Assisted Reproduction Technology (ART) reveals none that are sufficiently robust to justify its routine use. Data were evaluated for evidence that the use of TLI incubators results in improved treatment outcomes, whether through theoretically improved culture conditions (resulting from uninterrupted culture) or through theoretically improved embryo selection (resulting from the use of algorithms developed from analysis of time-lapse images of developing embryos), compared with using conventional incubation and conventional embryo selection methods. No such evidence is currently available.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Armstrong, S, Bhide, P, Jordan, V, Pacey, A, Marjoribanks, J, Farquhar, C. Time-lapse systems for embryo incubation and assessment in assisted reproduction. Cochrane Database Syst Rev. 2019; Issue 5. Art. No.: CD011320. DOI: 10.1002/14651858.CD011320.pub4.CrossRefGoogle Scholar
Pribenszky, C, Nilselid, A-M, Montag, M Time-lapse culture with morphokinetic embryo selection improves pregnancy and live birth chances and reduces early pregnancy loss: a meta-analysis. Reprod BioMed. Online 2017;35:511–20.CrossRefGoogle ScholarPubMed

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