Let A be a subset of a Banach space E. A mapping T: A →A is called asymptoically semicontractive if there exists a mapping S: A×A→A and a sequence (kn) in [1, ∞] such that Tx=S(x, x) for all x ∈A while for each fixed x ∈A, S(., x) is asymptotically nonexpansive with sequence (kn) and S(x,.) is strongly compact. Among other things, it is proved that each asymptotically semicontractive self-mpping T of a closed bounded and convex subset A of a uniformly convex Banach space E which satisfies Opial's condition has a fixed point in A, provided s has a certain asymptoticregurity property.