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Chapter 5a - Vaginal Aplasia: Creatsas Vaginoplasty
from Section 1 - Basic Sciences in Gynaecology
- By George K. Creatsas
Edited by Tahir Mahmood, Charles Savona-Ventura, Ioannis Messinis, Sambit Mukhopadhyay
Book:

The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology

Published online:

24 November 2021

Print publication:

02 December 2021, pp 44-46
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Summary

Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is a rare congenital abnormality of the female genital tract presenting with aplasia of the uterus and the upper two-thirds of the vagina in an otherwise normal 46XX individual. The incidence is approximately one case in 4000 women. The syndrome is frequently associated with other non-gynaecological defects, such as urinary tract anomalies, vertebral deformities and, to a lesser extent, auditory and cardiac lesions. The absence of the vagina and the uterus have a profound psychological impact on the young woman’s sense of femininity, so the demand for a sexual life makes the creation of a neovagina strongly advisable. Diagnosis is based on the history, the clinical and gynaecological examination, ultrasonography, including the urinary tract examination to exclude relative anomalies, and laparoscopy and hysteroscopy to diagnose and classify the relative uterovaginal anomaly.