The Çukurova Deltas on the southern coast of Turkey, with their high biodiversity, are one of the most important wetland and RAMSAR sites in the eastern Mediterranean basin. The total native flora comprises 600 plant taxa, including many endemic and threatened taxa. In an examination of this flora, 62 taxa (31 endemic and 31 rare taxa for Turkey) were categorized as having restricted distributions and being under threat of extinction. To assess the conservation status of the threatened flora, the IUCN Red List categories and criteria were applied at both a regional and global scale. The distribution of threatened flora in the study area was analysed in relation to four principle habitats: sand dunes (mobile or fixed) and sandy beaches (with 64.5% of all taxa), salt flats and salt water marshes (16.1%), river banks and fresh water marshes (9.7%), and field margins and roadsides (9.7%). Sand dunes and sandy beaches were identified as the most threatened habitats, being both sensitive to disturbance and heavily affected by humans. This Red Data List is a first step towards the recognition of conservation problems in the Çukurova Deltas and the need for more effective conservation of their flora.