Competition of weeds was characterized by determining the distance down the soybean row that a weed affects soybean biomass and yield. Field studies were conducted for 2 yr to compare competitive effects of common cocklebur, johnsongrass, Palmer amaranth, sicklepod, and tall morningglory on ‘Forrest’ and ‘Centennial’ soybeans. The weeds did not significantly reduce soybean biomass for 6 weeks after emergence. Palmer amaranth, common cocklebur, and tall morningglory had the greatest biomass by 6 weeks after emergence. However, only competition from common cocklebur and Palmer amaranth measurably reduced soybean biomass during the growing season. Biomass of Forrest and Centennial soybeans was reduced when these cultivars were growing within 12.5 and 50 cm of common cocklebur, respectively. Johnsongrass, sicklepod, and tall morningglory grew more slowly than the other weeds and had no measurable competitive effects on soybean biomass. Soybean competition reduced biomass of all weeds 90 to 97%. Soybean cultivar influenced the level and duration of competitiveness depending on the weed species present. Biomass of both soybean cultivars was reduced when they were growing within 50 cm of Palmer amaranth. Soybean seed yield was reduced when soybeans were growing within 25 cm of common cocklebur and Palmer amaranth and also when they were growing within 12.5 cm of tall morningglory. Sicklepod had no effect on soybean seed yield.