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In schizophrenia, the first contact with mental health services is frequently preceded by a lengthy, mostly untreated prephase. The few studies assessing the duration of the early period of illness from the first sign of the disorder until the first contact with mental health services give estimates ranging from two to almost nine years. This chapter focuses on when and with what symptoms does schizophrenia start, and explores how the disorder develops before the first episode. It analyses when and how does schizophrenia lead to social consequences and what are the implications for early intervention. The early course of schizophrenia, from the first prodromal sign until the climax of the first psychotic episode, seems to be a decisive period in the total course of the illness. Early detection and early intervention are therefore necessary and meaningful.
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