Smutgrass, a native of tropical Asia, is a perennial weed that affects many improved perennial grass pastures in Florida and throughout the southeastern United States. The two varieties of smutgrass predominant in Florida are small smutgrass and giant smutgrass. Three field experiments were conducted from 2008 to 2012 to evaluate the effect of integrated long-term management strategies using both cultural and herbicide inputs for giant smutgrass control in bahiagrass pastures. Burning did not have a significant impact on long-term control. In 2011, no differences were observed when hexazinone was integrated with tillage or hexazinone was combined with supplemental nitrogen compared with sequential or single applications of hexazinone. However, cultural treatments that preceded hexazinone application compared with those that received two sequential applications of hexazinone had lower smutgrass control 36 mo after treatment. Data indicate that a sequential application of hexazinone may be better than implementing tillage. Sequential hexazinone applications, when applied at 0.56 kg ai ha−1 or greater, resulted in similar or increased control as compared with single applications. Collectively, these data suggest that sequential applications of hexazinone may be most effective for smutgrass management, and cultural techniques, including tillage, should be followed by hexazinone application the following year.