We consider polynomial mappings which have atypical fibres due to the asymptotic behavior at infinity. Fixing some proper extension of the polynomial mapping, we study the localizability at infinity of the variation of topology of fibres and the possibility of interpreting local results at infinity into global results. We prove local and global Bertini–Sard–Lefschetz type statements for noncompact spaces and nonproper mappings and we deduce results on the homotopy type or the connectivity of the fibres of polynomial mappings.