Focussing on complete regularity, we discuss the separation properties of bitopological spaces. The unifying concept is that of separation by a pair of bases (B1, B2) for the closed sets of a bitopological space (S, J1, J2). For various separation properties a characterization is presented in terms of separation by a pair of closed bases. This is extended to results concerning pairs of subbases. Here the notion of screening by pairs of subbases plays a central role and the characterization of complete regularity in a natural way fits in between those of regularity and normality. In the key lemma the relation with quasi-proximities is exhibited.