Invariance criteria are widely accepted as a means to demarcate the logical vocabulary of a language. In previous work, I proposed a framework of “semantic constraints” for model-theoretic consequence which does not rely on a strict distinction between logical and nonlogical terms, but rather on a range of constraints on models restricting the interpretations of terms in the language in different ways. In this paper I show how invariance criteria can be generalized so as to apply to semantic constraints on models. Some obviously unpalatable semantic constraints turn out to be invariant under isomorphisms. I shall connect the discussion to known counter-examples to invariance criteria for logical terms, and so the generalization will also shed light on the current existing debate on logicality. I analyse the failure of invariance to fulfil its role as a criterion for logicality, and argue that invariance conditions should best be thought of as merely methodological meta-constraints restricting the ways the model-theoretic apparatus should be used.