Lepidopterous stem-borers are the most serious and widely distributed insect pests of sorghum. Among the several avenues of their control, the use of resistant varieties holds good prospects. In order to identify the sources of resistance to stem-borers (Chilo partellus, Busseola fusca, Eldana saccharina and Sesamia calamistis), a large number of sorghum lines from Kenya, India and Texas, U.S.A. have been screened under a very heavy natural infestation in Western Kenya. Several promising lines with resistance potential have been identified for the stem-borer complex which include: IS 10370, L-2 (TX 2780), IS 10364, IS 1044, S-178, IS 3962, IS 4213, IS 12447, IS 18479, IS 18326, L-l (A&B TX 2756), IS 4405, IS 10711, IS 18676, IS 5613, IS 18517, IS 18323, IS 4881, IS 1151 and IS 18427.