We determine the naturally reductive homogeneous real hypersurfaces in the family of curvature-adapted real hypersurfaces in quaternionic projective space HPn(n ≥ 3). We conclude that the naturally reductive curvature-adapted real hypersurfaces in HPn are Q-quasiumbilical and vice-versa. Further, we study the same problem in quaternionic hyperbolic space HHn(n ≥ 3).