This paper brings together several issues in Aquinas’s thought on God’s primary causality, providence, and the reading of scripture. Herein I argue that God’s primary causality is to be understood in terms of His being the source of all actuality. From there I go on to integrate Aquinas’s account of providence with the account of God’s primacy. With God’s primary causality and providence in place, I then go on to address the theme pertinent to this special edition, and that is God’s response to sin in Aquinas’s reading of scripture.