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1 results

  • Prehospital Treatment with Dobutamine

  • Bjarne Oberg, Mogens Bredgaard Sorensen
  • Journal:
    Prehospital and Disaster Medicine / Volume 8 / Issue 3 / September 1993
    Published online by Cambridge University Press:
    28 June 2012, pp. 247-249
    Print publication:
    September 1993
  • Purpose:

    To assess the effectiveness of the use of dobutamine hydrochloride in out-of hospital emergency situations.

    Population:

    Patients with severe circulatory insufficiency caused by acute illness or injury encountered by the Mobile Intensive Care Unit of Copenhagen (population 467,000) during a 15-month study period.

    Methods:

    A newly developed dobutamine solution was administered by infusion pump to patients in whom normal emergency treatment failed to restore an acceptable circulatory state.

    Results:

    A total of 40 patients were treated with 4–48 μg dobutamine/kg/minute. The treatment was judged to be primary life-saving in 15 patients, the condition was improved in 16 patients, and nine patients died. Systolic blood pressures (in those who survived) rose from a mean value of 45 mmHg (range 0–80 mmHg) to 105 mmHg (range 65–180 mmHg). No tachycardia or arrhythmias were noted.

    Conclusion:

    This newly developed dobutamine solution is very useful in prehospital treatment of patients with circulatory failure and is recommend for use by mobile intensive care unit teams.