Sounds produced by humans and their environment are perceived and codified based on people's experiences as members of social groups, resulting in some sounds being used as means of communication. In this article, we present an archaeoacoustic study of diverse types of instruments excavated or collected from Comalcalco and Jonuta, two important pre-Hispanic Maya sites located in the modern state of Tabasco (Mexico). We propose a methodology to analyze organological and acoustic characteristics for each type of instrument, considering their relevant archaeological information, so as to provide some interpretations of how sounds could have been materialized, shared, and used in specific moments of Maya ritual and daily life.