Inspired by the objectives of the Church of England’s Living Ministry Research Project (to understand the factors that enable clergy to flourish and to understand how these factors vary according to person, background, etc.), the present analyses were designed to test the capacity of an individual differences approach to the science of clergy well-being for delivering such objectives. The specific case in point concerned understanding the connections between migration to digital technology and changes in clergy well-being during the pandemic. The data demonstrated how the individual differences approach both offered explanatory power and provided insights into how personal support and professional development could be most effectively structured and targeted.