Adsorption and desorption characteristics of fluridone (1-methyl-3-phenyl-5-[3-txifluoromethyl)phenyl]-4-(1H)-pyridinone} on prepared clays and organic matter were studied in unbuffered and buffered aqueous solutions. In unbuffered aqueous solution the adsorption of fluridone decreased in the order: H-saturated organic matter (H-OM) > Ca-saturated montmorillonite (Ca-mont) > Ca-saturated organic matter (Ca-OM) > kaolinite. Based on the chemistry of fluridone, the nature of the adsorbent, and previously reported studies, the major adsorption mechanisms appear to be pH-dependent adsorption of protonated fluridone and direct protonation of the herbicide at acidic surfaces, supplemented by physical adsorption forces such as van der Waals attractions and charge transfer bonds. The adsorption of fluridone on Norfolk sand (Typic Paleudult; fine-loamy, siliceous, thermic), unmodified (CK), or amended with montmorillonite (HC) or organic matter (HM) at pH 4.0, 5.2, and 7.0 was also studied. Over all adsorption was greatest on HC soil, least on CK soil, and intermediate on the HM soil. In each system adsorption was inversely related to pH. These results were interpreted by comparison with adsorption observed on prepared clay minerals and organic matter.