Aspects of the distribution and ecology of ophiuroids from shallow waters off Maceió, State of Alagoas in north-eastern Brazil were characterized. The ophiuroid fauna comprised 16 species in nine genera and seven families, including three endemic species from Brazil, Ophiocnida loveni, Ophiactis brasiliensis and Amphiura kinbergi, and also four new records for the coastal reef system off north-eastern Brazil. On coral reefs 15 species were found and Ophiothrix angulata was the most abundant species. The sandstone reefs presented six species with dominance to Ophioderma appressa. Four of these species were associated with the fouling community on piers. Ophioderma appressa and Ophioderma cinerea were common in the intertidal zone on the reef edges and tide pools on coral reefs. The results demonstrated the presence of a large number of Ophiuroidea species in the shallow waters of Maceió, and expanded their distributions to the State of Alagoas and the reef systems of north-eastern Brazil.