A number field K with a ring of integers 𝒪K is called a Pólya field, if the 𝒪K-module of integer-valued polynomials on 𝒪K has a regular basis, or equivalently all its Bhargava factorial ideals are principal [1]. We generalize Leriche's criterion [8] for Pólya-ness of Galois closures of pure cubic fields, to general S3-extensions of ℚ. Also, we prove for a real (resp. imaginary) Pólya S3-extension L of ℚ, at most four (resp. three) primes can be ramified. Moreover, depending on the solvability of unit norm equation over the quadratic subfield of L, we determine when these sharp upper bounds can occur.