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Section 5 - Lymphatic System
from Part 3 - Systems Based Overview of Cancer Complications
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 173-210
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 49 - Tumor Lysis Syndrome
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

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24 August 2023, pp 207-210
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 45 - Differentiation Syndrome in Acute Leukemias
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 185-188
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 47 - Hyperleukocytosis and Leukostasis
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 195-198
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 44 - Checkpoint Inhibitor Immune Related Adverse Events
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 177-184
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 48 - Neutropenic Fever
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 199-206
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 46 - Graft versus Host Disease
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 189-194
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Chapter 43 - Chimeric Antigen Receptor (CAR) T-Cell Toxicity
from Section 5 - Lymphatic System
Monica Kathleen Wattana, University of Texas, MD Anderson Cancer Center
Book:

Pocket Guide to Oncologic Emergencies

Published online:

10 August 2023

Print publication:

24 August 2023, pp 173-176
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Summary

Overview of toxicities related to immunotherapy agents, and other complications in the lymphatic system such as tumor lysis, hyperviscosity syndrome, graft vs host disease, and neutropenic fever

Section 12 - End of life
Edited by Kaushal Shah, Jarone Lee, Kamal Medlej, American University of Beirut, Scott D. Weingart
Book:

Practical Emergency Resuscitation and Critical Care

Published online:

05 November 2013

Print publication:

24 October 2013, pp 451-456
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Summary

This chapter discusses the diagnosis, evaluation and management of neutropenic fever. The initial presentation of the critically ill with neutropenic fever may be overt with a clinical presentation similar to that of septic shock and including hypotension, respiratory failure, or any other major organ dysfunction. It may also be cryptogenic with isolated confusion, coagulopathy, or cardiac arrhythmias. Elderly patients and those taking steroids may present as hypothermic or euthermic. Any unexplained acute clinical deterioration should be considered a fever equivalent. Critically ill patients with neutropenic fever will most frequently present with common infections. However, their immunocompromised state places them at risk for more complex disease processes of almost any organ system. The pathophysiology of the decompensating patient with neutropenic fever is similar to that of a patient in septic shock. Those patients should be resuscitated similarly by the rapid and aggressive administration of crystalloids.

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