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The purpose of this study was to compare the self- and observer ratings of capacity limitations in patients with neurological conditions. Research on this topic is relevant for assessing the patients’ ability to participate in work and social life and improving collaborative patient-clinician relationships.
Method:
The self- and observer ratings of capacity limitations in a sample of N = 245 patients with neurological conditions from a rehabilitation facility were compared and assessed using the short rating of activity limitations and participation restrictions in mental disorders according to the International Classification of Functioning, Disability and Health (Mini-ICF-APP) and the equivalent self-rating questionnaire (Mini-ICF-APP-S).
Results:
Paired-samples t-tests revealed significant differences between the self- and observer ratings for six out of 13 capacity dimensions. On average, the patients rated the capacity dimensions adherence to regulations, planning and structuring of tasks, professional competency and endurance as significantly less limited, in comparison to the observers (small to medium effect sizes). The self-ratings for limitation of contact with others and self-care were only marginally higher than the observer ratings.
Conclusions:
The findings show that psychological capacity limitations occur in patients with neurological conditions. In clinical practice, limitations in each capacity dimension and discrepancies in patient- and clinician-ratings should be thoroughly assessed. This is especially relevant in patients with neurological conditions who have a potential tendency to underestimate or deny their disability.
Scientific discovery and clinical investigation are critical for developing and evaluating new treatments and can have substantial public health benefits. A detailed analysis of clinical trials funded by the National Institute of Neurological Disorders and Stroke found that the public return on investment in clinical trials has been substantial. In addition to the inherent risks involved in clinical trials, the challenges of translating scientific advances into new therapeutic advances are increasing. Many of the challenges of drug development are particularly acute for treatments of neurological conditions. The scope of clinical trials for neurological conditions is rapidly expanding to address orphan indications, biologics, medical devices, surgeries, and comparative effectiveness studies. In addition to drugs, clinical trials frequently evaluate devices for neurological conditions. High quality data on surgical interventions, such as temporal lobe resections for epilepsy are critical to understanding their relative risks and benefits in the target populations.
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