Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

2 results

  • Double Dissociation of Auditory Attention Span and Visual Attention in Long-Term Survivors of Childhood Cerebellar Tumor: A Deterministic Tractography Study of the Cerebellar-Frontal and the Superior Longitudinal Fasciculus Pathways

  • Alyssa S. Ailion, Tricia Z. King, Simone R. Roberts, Brian Tang, Jessica A. Turner, Christopher M. Conway, Bruce Crosson
  • Journal:
    Journal of the International Neuropsychological Society / Volume 26 / Issue 10 / November 2020
    Published online by Cambridge University Press:
    28 April 2020, pp. 939-953
  • Objective:

    Right cerebellar-left frontal (RC-LF) white matter integrity (WMI) has been associated with working memory. However, prior studies have employed measures of working memory that include processing speed and attention. We examined the relationships between the RC-LF WMI and processing speed, attention, and working memory to clarify the relationship of RC-LF WMI with a specific cognitive function. Right superior longitudinal fasciculus II (SLF II) WMI and visual attention were included as a negative control tract and task to demonstrate a double dissociation.

    Methods:

    Adult survivors of childhood brain tumors [n = 29, age: M = 22 years (SD = 5), 45% female] and demographically matched controls were recruited (n = 29). Tests of auditory attention span, working memory, and visual attention served as cognitive measures. Participants completed a 3-T MRI diffusion-weighted imaging scan. Fractional anisotropy (FA) and radial diffusivity (RD) served as WMI measures. Partial correlations between WMI and cognitive scores included controlling for type of treatment.

    Results:

    A correlational double dissociation was found. RC-LF WMI was associated with auditory attention (FA: r = .42, p = .03; RD: r = −.50, p = .01) and was not associated with visual attention (FA: r = −.11, p = .59; RD: r = −.11, p = .57). SLF II FA WMI was associated with visual attention (FA: r = .44, p = .02; RD: r = −.17, p = .40) and was not associated with auditory attention (FA: r = .24, p = .22; RD: r = −.10, p = .62).

    Conclusions:

    The results show that RC-LF WMI is associated with auditory attention span rather than working memory per se and provides evidence for a specificity based on the correlational double dissociation.

  • 21 - Neurocognitive outcome in children of mothers with epilepsy

  • from Part V - Family planning, pregnancy, and parenting
    • By Kimford J. Meador, Department of Neurology, Georgetown University Hospital, 3800 Reservoir Road, NW, Washington DC 20007, USA
  • Edited by Martha J. Morrell, Columbia University, New York, Kerry L. Flynn, Columbia-Presbyterian Cancer Center, New York
  • Book:
    Women with Epilepsy
    Published online:
    02 November 2009
    Print publication:
    20 March 2003, pp 222-227

  • Summary

    This chapter reviews what one knows about the neurological and cognitive effects of antiepileptic drugs (AEDs) on the developing fetus. The combined effects and interactions of genes and the environment determine neurodevelopment. Thus, a child's neurodevelopment is affected by that child's inheritance, the mother's age at the time of pregnancy, the child's birth order, the mother's health during the pregnancy, drug exposure, obstetric complications, the nutritional status of the mother and child, childhood illnesses, social and economic status of the family, the mother's and father's educational levels, as well as the child's educational opportunities. A variety of factors may contribute to the neurodevelopmental deficits observed in the children of women with epilepsy. Children born to mothers with epilepsy have a slightly higher risk of neurodevelopmental difficulties, which can be reduced by good health practices, good seizure control, and using only as much antiepileptic medication as is necessary for seizure control.