Laser metal deposition (LMD) additive manufacturing was used to deposit Inconel 625 matrix composites reinforced with nano-TiC particles. The effects of laser energy input per unit length (E) on the densification level, microstructural features, mircohardness, and wear property were investigated. The relatively low E induced insufficient liquid with higher viscosity, thus inhibiting the melted liquid from spreading out smoothly. As a result, a large number of micropores and reduced densification level of LMD-processed parts were obtained. When the E of 100 kJ/m was properly settled, the obtainable densification level generally approached 98.8%. The TiC reinforcements experienced successive microstructural changes from agglomeration to uniform distribution with coarsening grain, as the applied E increased. The nearly fully dense parts using optimal experimental parameters achieved an increased average microhardness of 330 HV0.2, resultant considerably low coefficient of friction of 0.41 and reduced wear rate of 5.4 × 10−4 mm3/(N m) in dry sliding wear tests.