The principle of independence is central to the International Red Cross and Red Crescent Movement's work with and for migrants. Independence requires humanitarian actors to retain their autonomy and resist any interference that might divert them from acting according to the principles of humanity, impartiality and neutrality. Yet, in the face of increasing securitization of migration and instrumentalization of aid and migrants, independence – in practice and perception – cannot be assumed. Drawing from current debates and primary research by the Red Cross Red Crescent Global Migration Lab, this article examines existing challenges in upholding independence in migration contexts and outlines recommendations for action.