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Reviews in Clinical Gerontology (1)

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Recent clinical trials in diabetes – implications for managing older patients
Part of
- Bespoke shallow archive Weizmann
GC Hawthorne, AJ Yarnall
Journal:

Reviews in Clinical Gerontology / Volume 19 / Issue 1 / February 2009

Published online by Cambridge University Press:

17 August 2009, pp. 25-33

Print publication:

February 2009
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The prevalence of type 2 diabetes is set to increase, and with it the complications associated with diabetes. Since 2007 there have been a number of significant trials that may change the way we think about treating people with diabetes, especially our older patients. These trials include the Steno-2 trial, UKPDS legacy trial, ADVANCE, ACCORD and VADT. These trials are reviewed in detail in this article, including the implications for the patients we treat. Recent work assessing the effect of HbA1c on cognitive function and the effects of hypoglycaemia are also discussed. We conclude with suggestions for targets for glycated haemoglobin level based on NICE guidance.