Meadow foxtail is a rhizomatous grass widely grown for hay and pasture in wet meadows of the western United States and Canada. Two sulfonylurea herbicides, chlorsulfuron and metsulfuron-methyl, were evaluated for their effects on meadow foxtail biomass. Both herbicides were applied at four doses, 0.035, 0.070, 0.105, and 0.140 kg ai/ha, together with a control at each of two sites in October 2003. Treatments were replicated four times at each site and arranged in a randomized complete block design and sampled in July 2004 and 2005. Meadow foxtail biomass depended on site (P = 0.001) or year (P = 0.001), but not herbicide treatment (P = 0.182). No biomass production losses resulted from applying up to 0.14 kg/ha of either chlorsulfuron or metsulfuron-methyl on meadow foxtail, even in relatively high-pH soils.