A survey conducted across agricultural ecoregions of Saskatchewan in 1996 revealed that wild oat (Avena fatua) populations resistant to acetyl-CoA carboxylase (ACCase) inhibitors were present in approximately 10% of Saskatchewan fields (2.4 million ha). In the Aspen Parkland and Boreal Transition ecoregions, this increased to 17%. The objective of this study was to determine if agronomic practices promoted or delayed resistance and to assess producer awareness of herbicide resistance. Weed resistance and management questionnaire data from the 1996 resistance survey and management questionnaire data from the 1995 Saskatchewan weed survey were submitted to multiway frequency analysis. The frequency of occurrence of herbicide-resistant wild oat was related directly to ACCase inhibitor use. Resistance to cyclohexanedione (CHD) herbicides was not related to CHD use but to frequency of ACCase inhibitor use (i.e., CHD + aryloxyphenoxypropanoate [AOPP]), suggesting that the pressure imposed by AOPPs contributed to the selection of CHD resistance in wild oat. ACCase inhibitor use was more extensive in the Aspen Parkland and Boreal Transition ecoregions than in the Mixed and Moist Mixed Grassland ecoregions. Crop rotations were not conducive to rotation of herbicides with different sites of action. Frequency of ACCase inhibitor use increased with frequency of annual crops, in spite of the inclusion of cereal and dicot crops in the rotation. Producers utilizing conservation tillage practices in the Grassland ecoregions used proportionally more ACCase inhibitors than those using conventional tillage practices. This increase in ACCase use in conservation tillage systems did not result in an increased incidence of wild oat populations resistant to ACCase inhibitors. Producers reporting troublesome wild oat populations tended to have proportionally more ACCase-resistant wild oat. Producers who reported practicing weed sanitation were less likely to have resistant wild oat than those who were less careful. Increased awareness and implementation of management practices that will reduce the dependency on ACCase herbicides are required to better enable producers to prevent, delay, or manage herbicide-resistant wild oat populations.