We prove two theorems concerning indestructibility properties of the first two strongly compact cardinals when these cardinals are in addition the first two measurable cardinals. Starting from two supercompact cardinals $\kappa _1 < \kappa _2$ , we force and construct a model in which $\kappa _1$ and $\kappa _2$ are both the first two strongly compact and first two measurable cardinals, $\kappa _1$ ’s strong compactness is fully indestructible (i.e., $\kappa _1$ ’s strong compactness is indestructible under arbitrary $\kappa _1$ -directed closed forcing), and $\kappa _2$ ’s strong compactness is indestructible under $\mathrm {Add}(\kappa _2, \delta )$ for any ordinal $\delta $ . This provides an answer to a strengthened version of a question of Sargsyan found in [17, Question 5]. We also investigate indestructibility properties that may occur when the first two strongly compact cardinals are not only the first two measurable cardinals, but also exhibit nontrivial degrees of supercompactness.