Breed performs a central concept for animal science. It is used to define subdivisions of domestic species. This work analyses the evolution through time of breed concept, and the impact of science on breed evolution. Domestication effects are discussed from genetic point of view and breeds were classified as: primary, secondary, synthetic or mendelian. The concept was analysed within South American domestic camelids in which only primary breeds exist. Misleading concepts on Suri alpacas, white coated llamas-alpacas and pure breeds were also clarified. It was finally concluded that some private enterprise, NGO's and public organisations must follow the practical steps of selection to maintain the breed standards of llamas and alpacas.