Field experiments were conducted to evaluate the interactions of tillage systems with imazaquin and imazethapyr on weed control and soybean injury and yield. Control of jimsonweed, common cocklebur, ivyleaf morningglory, velvetleaf, and giant foxtail from imazaquin and imazethapyr in conventional tillage was generally equal to or greater than control in no-tillage. However, under limited rainfall, weed control in no-tillage was generally equal to or greater than control in conventional tillage. Reductions in soybean heights due to herbicide treatment were evident in both tillage systems in 1985 and 1986 but not in. Soybean yields were reduced in 1985 from imazaquin at 140, 210, and 250 g/ha and imazethapyr at 105 and 140 g/ha. Yields were not reduced in 1986 and. Imazaquin and imazethapyr appear to provide adequate control of jimsonweed, common cocklebur, ivyleaf morningglory, velvetleaf, and giant foxtail in conventional and no-till systems.