Cocaine is increasingly used on a recreational basis by the general population with potential implications for mental health. The aim of this study was to assess how common cocaine use is, and its mental health associations, in a large sample of university students.

Approximately 10 000 university students were invited to take part in an online survey, which assessed the use of cocaine (ever or past year), alcohol and drug use, mental health issues, and impulsive and compulsive tendencies. Group differences in demographic and clinical characteristics were characterized.

A total of 3520 university students (57.7% female) completed the survey. Of these, 110 students (3.1%) reported using cocaine in the preceding year, and a further 163 students (4.6%) reported historical use more than a year ago. Cocaine use was associated with more years as a student, lower grade point averages, more use of other drugs, riskier sexual practices, post-traumatic stress disorder, attention deficit hyperactivity disorder, treatment for psychological/emotional problems (including taking prescribed medication), and trait impulsivity. Of these associations, the link with trait impulsivity had the largest effect size.

History of cocaine use appears relatively common in university students; and has a number of untoward associations in terms of mental health, use of other substances, and risky sexual practices. The most marked finding (in terms of effect size) was the link between cocaine use and trait impulsivity, supporting the importance of this construct in seeking out candidate vulnerability markers for use of cocaine and other drugs. Future work should use longitudinal designs to further characterize the nature of these associations.